The Effect of Anakinra on Acrylamide-induced Peripheral Neuropathy and Neuropathic Pain in Rats
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Abstract Acrylamide is a neurotoxic compound. Moreover, anakinra is an interleukin-1 (IL-1) receptor antagonist used in rheumatoid arthritis treatment. This study investigated the effect of anakinra on acrylamide-related neuropathy and neuropathic pain. Acrylamide exposure caused a significant decrease ...
Acrilamida/efectos adversos, Estrés Oxidativo/efectos de los fármacos, Inflamación/clasificación, Artritis Reumatoide/patología, Enfermedades del Sistema Nervioso Periférico/patología, Factor de Necrosis Tumoral alfa/farmacología, Umbral del Dolor/clasificación, d0125840, Nervios Periféricos/anomalías, Proteína Antagonista del Receptor de Interleucina 1/antagonistas & inhibidores