Results: 5

Cut-off values of immunological tests to identify patients at high risk of severe lupus nephritis

Medicina (B.Aires); 78 (5), 2018
Cut-off values for anti-dsDNA, anti-nucleosome and anti-C1q antibodies tests and for complement-mediated hemolytic activity (CH50) were explored to identify patients with high risk of developing severe lupus nephritis (LN). Forty-one patients with confirmed systemic lupus erythematosus (SLE) were identif...

Synthesis and in silico study of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives as suitable therapeutic agents

Abstract In the study presented here, a new series of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives was targeted. The synthesis was initiated by the treatment of different secondary amines (1a-h) with 4-bromomethylbenzenesulfonyl chloride (2) to obtain various 1-{[4-(bro...

Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1, 3, 4-oxadiazol-2-yl]sulfanyl}acetamides as suitable therapeutic agents

Braz. j. pharm. sci; 51 (4), 2015
abstract A series of N-substituted 2-{[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides (8a-w) was synthesized in three steps. The first step involved the sequential conversion of 2-(1H-indol-3-yl)acetic acid (1) to ester (2) followed by hydrazide (3) formation and finally cyclization in ...

Producción de un anticuerpo de conejo anti-glóbulos rojos de carnero para utilizarlo en la valoración de la Actividad Hemolítica del Complemento (CH50)
Production of an anti-ram erythrocite rabbit antibody for use in haemolytic activity assessment of CH 50 complement

Gac. méd. espirit; 4 (SUP 4), 2002
La valoración de la Actividad Hemolítica del Complemento (CH50) constituye un medio diagnóstico en el que se mide la capacidad de la vía clásica del complemento para lisar eritrocitos de carnero óptimamente sensibilizados con un anticuerpo anti-eritrocitos de carnero (hemolisina), cuya actividad es...

Investigaçäo sorológica da influenza tipos A e B em estudantes universitários, Brasil
Serological investigation of influenza type A and B in university students

Rev. saúde pública; 25 (6), 1991
Levantamento sorológico realizado em 200 estudantes da Universidade de Säo Paulo, nos anos de 1984 e 1985, demonstrou ampla prevalência sorológica do vírus da influenza tipos A e B. Os anticorpos dos indivíduos foram detectados pela técnica de Hemólise Radial Simples (HRS), cujas médias aritmét...