Establishment of patient-derived tumor xenograft (PDTX) models using samples from CT-guided percutaneous biopsy
Braz. j. med. biol. res; 50 (6), 2017
This study aimed to investigate the feasibility of the establishment of a human cancer xenograft model using samples from computed tomography (CT)-guided percutaneous biopsy. Fresh tumor tissues obtained from 10 cancer patients by CT-guided percutaneous biopsy were subcutaneously inoculated into NOD-Prkd...
Adenocarcinoma/patología, Antineoplásicos/farmacocinética, Desoxicitidina/análogos & derivados, Desoxicitidina/farmacocinética, Modelos Animales de Enfermedad, Estudios de Factibilidad, Biopsia Guiada por Imagen/métodos, Neoplasias Hepáticas/patología, Neoplasias Pulmonares/patología, Ratones Endogámicos, Compuestos Organoplatinos/farmacocinética, Tomografía Computarizada por Rayos X, Ensayos Antitumor por Modelo de Xenoinjerto/instrumentación, Ensayos Antitumor por Modelo de Xenoinjerto/métodos