Preparation and evaluation of 2-methoxyestradiol-loaded pH-sensitive liposomes
Braz. J. Pharm. Sci. (Online); 55 (), 2019
The development and clinical application of 2-methoxyestradiol (2-ME) as a new type of antitumor drug are limited due to its poor solubility, rapid metabolism in vivo, and large oral dosage. 2-ME-loaded pH-sensitive liposomes (2-ME-PSLs) was prepared containing the lipids, Lipoid E-80 (E-80), cholesteryl...