Results: 12

Reduced naïve T cell numbers correlate with increased low-grade systemic inflammation during ageing and can be modulated by physical activity

Int. j. morphol; 39 (3), 2021
SUMMARY: Age-associated decline of immune system, termed immunosenescence, is characterized by low-grade systemic inflammation, known as inflammaging, together with T-cell functional dysregulation. Although affecting all individuals, different environmental as well genetic factors impinge on the individu...

Definición de caso COVID-19: ¿Debe ser la misma para el adulto mayor?
COVID-19 case fefinition: should it be the same for the older adult?

A propósito del Covid-19. El rol de la edad y género en la inmunidad
About the Covid-19. The role of age and gender in immunity

The purpose of the immune system is to protect the body from pathogenic microorganisms such as bacteria, viruses, fungi and even tumor cells, which could cause disease. When the encounter with pathogens occurs, defenses are produced immediately through the innate response, faster and more nons...

Immunosenescence: participation of T lymphocytes and myeloid-derived suppressor cells in aging-related immune response changes

Einstein (Säo Paulo); 17 (2), 2019
ABSTRACT Healthy aging is partly related to appropriate function of the immune system. As already reported, some changes in this system are observed, including reduced number and repertoire of T cells due to thymic involution, accumulation of memory T cells by chronic infections, homeostatic proliferatio...

Time-course of health-related adaptations in response to combined training in hypertensive elderly: immune and autonomic modulation interactions

Motriz (Online); 24 (4), 2018
This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Met...

Dermatopatías [Comentarios del director]
Dermatopathies [Comments of the director]

Rev. chil. dermatol; 17 (2), 2001

Envejecimiento vs. radicales libres
Free radicals vs. aging

Los radicales libres se han visto implicados en más de 100 enfermedades tanto humanas como animales, desde artritis reumatoide y shock hemorrágico hasta Sida. Actualmente se estudia su importancia en los procesos de envejecimiento celular, ya que cualquier deficiencia en el sistema antioxidante provoca...

Toxicidad neuronal de la interleucina-2 recombinante humana en ratas: validación morfoconductual

Introducción y objetivo. La afectación de memoria que se observa en el envejecimiento es una manifestación de la disminución de las funciones cognitivas con la edad, la cual está estrechamente asociada a cambios neuropatológicos y bioquímicos en áreas colinérgicas del sistema nervioso central (S...