SUMMARY OBJECTIVE: Epilepsy is a common disorder that affects the nervous systems of 1% of worldwide population. In epilepsy, one-third of patients are unresponsive to current drug therapies and develop drug-resistant epilepsy. Alterations in ghrelin, nesfatin-1, and irisin levels with epilepsy were rep...
Mesial temporal lobe epilepsy is the most commom form of focal epilepsy in adults. Its clinical features include focal seizure, dysmnestic symptoms – such as déjà vu or jamais vu – and autonomic or psychic aura. We reported two cases of mesial temporal lobe epilepsy with similar clinical features, ...
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the predominant mediators of glutamate-induced excitatory neurotransmission. It is widely accepted that AMPA receptors are critical for the generation and spread of epileptic seizure activity. Dysfunction of AMPA receptors as ...
ABSTRACT Sleepiness and cognitive impairment are common symptoms observed in patients with epilepsy. We investigate whether self-reported sleepiness is associated with cognitive performance in patients with refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). Seventy-one consecu...
Objetivos: O tratamento inicial de pacientes com epilepsia do lobo
temporal é feito com drogas antiepilépticas, porém grande parte destes
apresenta epilepsia refratária aos medicamentos e, portanto, devem ser
avaliados para cirurgia de ressecção. Para tanto, este artigo fornece informações
para a...
