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Reporte en Chile de pacientes pediátricos con síndrome de Dravet y confirmación genética de mutaciones en la subunidad alfa del canal de sodio neuronal dependiente de voltaje tipo 1

Dravet syndrome (DS) is a rare epileptic encephalopathy. It starts with febrile seizures, followed by different types of seizures, refractory to treatment and associated with cognitive impairment. Sodium channel, voltage-gated type I, alpha subunit (SCN1A) mutation is detected in about 80% of subjects. O...