Can paricalcitol increase the effectiveness of n-acetylcysteine in contrast induced acute kidney prophylaxis in rats? A biochemical and histopathological study
Int. j. morphol; 40 (4), 2022
SUMMARY: N-Acetylcysteine (NAC) is used for contrast induced acut kidney injury (CI-AKI) prophylaxis because of its antioxidant effects. Paricalcitol, which has reno-protective effects, is likely to provide a more effective prophylaxis when added to NAC treatment. The study was designed based on this hyp...
Lesión Renal Aguda/prevención & control, Lesión Renal Aguda/inducido químicamente, Medios de Contraste/efectos adversos, Ergocalciferoles/administración & dosificación, Ergocalciferoles/farmacología, Acetilcisteína/administración & dosificación, Acetilcisteína/farmacología, Antioxidantes/administración & dosificación, Antioxidantes/farmacología, Estrés Oxidativo/efectos de los fármacos, Ratas Wistar