Vegetable extracts have become important raw materials for food, pharmaceutical and cosmetic industries because of their biological potential. The objective of this study was to assess the biological activity of vegetable oils (VOs) extracted from Annona muricata...
Annona/química,
Aceites de Plantas/farmacología,
Aceites de Plantas/química,
Antibacterianos/farmacología,
Plantas Medicinales,
Antibacterianos/química,
Semillas,
Bacterias/efectos de los fármacos,
Fitosteroles/análisis,
Cromatografía de Gases y Espectrometría de Masas,
Pruebas de Sensibilidad Microbiana,
Eritrocitos/efectos de los fármacos,
Metaloproteinasa 9 de la Matriz,
Neutrófilos/enzimología
Plant species have been used for therapeutic purposes since ancient times and are still in use today since these products represent a source of raw material for the production of phytotherapeutic formulations. Screening and investigation of plants with pharmacological potential require the evaluation of ...
Extractos Vegetales/toxicidad,
Eritrocitos/efectos de los fármacos,
Bioensayo/métodos,
Eritrocitos/citología,
Fragilidad Osmótica,
Estrés Oxidativo,
Bioprospección,
Antioxidantes/toxicidad,
Hemólisis/efectos de los fármacos,
Extractos Vegetales/toxicidad,
Eritrocitos/efectos de los fármacos,
Bioensayo/métodos,
Eritrocitos/citología,
Fragilidad Osmótica,
Estrés Oxidativo,
Bioprospección,
Antioxidantes/toxicidad,
Hemólisis/efectos de los fármacos
ABSTRACT Objective Hyperthyroidism causes many injuries in its target organs and the consequences are reflected systemically. As systemic alterations in hyperthyroidism at earlier stages have received partial attention, this study aimed to investigate systemic redox and inflammatory status at an early ...
Antioxidantes/metabolismo,
Modelos Animales de Enfermedad,
Eritrocitos/efectos de los fármacos,
Eritrocitos/metabolismo,
Hipertiroidismo/sangre,
Hipertiroidismo/metabolismo,
Oxidación-Reducción,
Estrés Oxidativo/efectos de los fármacos,
Pentosas,
Ratas Wistar,
Tiroxina
Abstract Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study was to evaluate the antifungal effect of the combination of amp...
ABSTRACT Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the...
ResumenLa producción agrícola de monocultivo permanente de banano y plátano en la parte media del Río Grande (Turbo - Antioquia) requiere de la aplicación de diferentes plaguicidas. Prácticas inapropiadas en la producción y cultivos de plátano realizadas en esta región a menudo conllevan a conta...
Characidae/sangre,
Colombia,
Monitoreo del Ambiente/métodos,
Eritrocitos/efectos de los fármacos,
Pruebas de Micronúcleos,
Plaguicidas/toxicidad,
Ríos/química,
Estaciones del Año,
Estadísticas no Paramétricas,
Contaminación Química del Agua/análisis,
Factores de Tiempo
Abstract Objective To evaluate whether patient age has a significant impact on mefloquine concentrations in the plasma and erythrocytes over the course of treatment for uncomplicated falciparum malaria. Methods A total of 20 children aged between 8 and 11 years and 20 adult males aged between 22 and 41...
Enfermedad Aguda,
Factores de Edad,
Antimaláricos/sangre,
Cromatografía de Fase Inversa,
Eritrocitos/efectos de los fármacos,
Malaria Falciparum/sangre,
Malaria Falciparum/tratamiento farmacológico,
Mefloquina/sangre,
Plasma,
Valores de Referencia,
Estadísticas no Paramétricas,
Factores de Tiempo
ABSTRACT Lectins are non-immunogenic carbohydrate-recognizing proteins that bind to glycoproteins, glycolipids, or polysaccharides with high affinity and exhibit remarkable ability to agglutinate erythrocytes and other cells. In the present study, ten Fusarium species previously not explored for lectins ...
BACKGROUND: Novel, in silico-designed anticancer compounds were synthesized in our laboratory namely, 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16). These compounds were designed to have improved bioavailability when com...
Antineoplásicos/farmacología,
Inhibidores de Anhidrasa Carbónica/farmacología,
Simulación por Computador,
Eritrocitos/efectos de los fármacos,
Estradiol/análogos & derivados,
Estrenos/farmacología,
Sulfonamidas/farmacología,
Antineoplásicos/farmacocinética,
Anhidrasa Carbónica II/efectos de los fármacos,
Inhibidores de Anhidrasa Carbónica/farmacocinética,
Proteínas Portadoras/farmacocinética,
Proteínas Portadoras/farmacología,
Eritrocitos/ultraestructura,
Estradiol/farmacocinética,
Estradiol/farmacología,
Estradiol/toxicidad,
Estrenos/farmacocinética,
Hemólisis/efectos de los fármacos,
Sulfonamidas/farmacocinética,
Sulfonamidas/toxicidad,
Disponibilidad Biológica,
Descubrimiento de Drogas,
Microscopía Electrónica de Rastreo,
Investigación Cualitativa,
Temperatura
