Results: 10

The impact of multiple sclerosis on the size and morphology of corpus callosum: an MRI-based retrospective study

Int. j. morphol; 41 (2), 2023
SUMMARY: The corpus callosum (CC) includes the majority of fibers linking the two brain hemispheres. Several cross sectional studies showed an association between callosal atrophy and malfunction and neurodegenerative diseases, which may play a role in their pathological manifestations. As a result, the ...

HLA-DQA1*04: 01 is related to a higher multiple sclerosis lesion load on T2/Flair MRI sequences

Arq. neuropsiquiatr; 79 (12), 2021
ABSTRACT Background: The genetic predisposition to multiple sclerosis (MS) is associated with HLA alleles, especially HLA-DRB1*15:01. Objective: To identify associations between findings in magnetic resonance imaging (MRI) and genetic features in a Brazilian cohort of patients with MS. Methods: We retros...

Valor pronóstico del glutamato en el líquido cefalorraquídeo en esclerosis múltiple

Medicina (B.Aires); 81 (5), 2021
Resumen El objetivo del trabajo fue evaluar la asociación entre el nivel de glutamato en el líquido cefalorraquídeo (LCR) al inicio de la enfermedad y la progresión de la enfermedad durante el seguimiento en una cohorte de pacientes con esclerosis múltiple (EM). Se determinaron niveles de glutamato ...

Regional brain atrophy is related to social cognition impairment in multiple sclerosis

Arq. neuropsiquiatr; 79 (8), 2021
ABSTRACT Background: Multiple sclerosis exhibits specific neuropathological phenomena driving to both global and regional brain atrophy. At the clinical level, the disease is related to functional decline in cognitive domains as the working memory, processing speed, and verbal fluency. However, the comp...

Enfermedades desmielinizantes en niños: Encefalomielitis diseminada aguda y esclerosis múltiple
Demyelinizing diseases in children. Acute disseminated encephalomyelitis and multiple sclerosis

Medicina (B.Aires); 79 (supl.3), 2019
Se revisan dos de las principales enfermedades desmielinizantes en niños, la encefalomielitis aguda diseminada (EAD) y la esclerosis múltiple (EM). Por sus características fisiopatológicas, etiologías probables, manifestaciones clínicas, diagnóstico, tratamiento, pronóstico, evolución, así como...

Ensayo pictórico: diagnóstico diferencial radiológico en esclerosis múltiple

Rev. chil. radiol; 25 (1), 2019
La esclerosis múltiple (EM) es la enfermedad inflamatorio-desmielinizante del Sistema nervioso central más prevalente en adultos. La resonancia magnética (RM) juega un rol cada vez más importante en el estudio de esta patología, en especial en su diagnóstico precoz, por lo que la diferenciación im...

Critical analysis on the present methods for brain volume measurements in multiple sclerosis

Arq. neuropsiquiatr; 75 (7), 2017
ABSTRACT Objective The treatment of multiple sclerosis (MS) has quickly evolved from a time when controlling clinical relapses would suffice, to the present day, when complete disease control is expected. Measurement of brain volume is still at an early stage to be indicative of therapeutic decisions i...

Benign multiple sclerosis: aspects of cognition and neuroimaging

Arq. neuropsiquiatr; 75 (6), 2017
ABSTRACT The existence of a benign multiple sclerosis (BMS) form is a controversial subject. Recent studies of these patients reveal different levels of cognitive impairment, despite the apparent preservation of motor function. The objective of this study was to review and analyze a number of publication...

Uso de volumetría y carga lesional en el seguimiento de pacientes con esclerosis múltiple: experiencia local y revisión de la literatura

Rev. chil. radiol; 19 (4), 2013
Multiple sclerosis (MS) is a common demyelinating disease that involves the central nervous system causing focal lesions in the brain and spinal cord causing diverse neurological development deficits, many of them severe and irreversible, affecting and invaliding a large percentage of young productive-ag...