ABSTRACT Objective: To analyze the molecular composition of a sample of Baltic amber taken from an amber bracelet, verify the presence or absence of compounds beneficial to human health, and discuss the therapeutic potential of this fossil resin. Material and Methods: For this, a qualitative analysis w...
Os sintomas depressivos durante a gravidez e o período pós-parto (PP) são prevalentes e podem ter implicações profundas para o bem-estar materno e infantil. Evidências emergentes sugerem que a microbiota intestinal pode desempenhar um papel na regulação do humor. Este estudo explora a relação e...
Microbioma Gastrointestinal/inmunología,
Embarazo,
Depresión/patología,
Bienestar Materno/clasificación,
Bienestar del Lactante/clasificación,
Bifidobacterium/inmunología,
Cromatografía de Gases/instrumentación,
Cromatografía de Gases y Espectrometría de Masas/métodos,
Derivación y Consulta/clasificación,
Espectrometría de Masas/métodos,
Hospitales/clasificación,
Obstetricia/clasificación
Abstract n our study, we aimed to validate a method based on liquid chromatography-mass spectrometry (LC-MS) to quantify spironolactone (SPI) and its active metabolite canrenone (CAN) simultaneously in plasma samples to support in vivo experiments. Compounds were separated by using a C18 column with the ...
Com base nas perturbações fosfoproteômicas de moléculas associadas ao ciclo celular em células infectadas pelo coronavírus causador da síndrome respiratória aguda grave (SARSCoV)-2, a hipótese de inibidores do ciclo celular como uma terapia potencial para a doença de coronavírus 2019 (COVID-19...
Ciclo Celular/inmunología,
Pacientes/clasificación,
COVID-19/patología,
Proteoma/análisis,
Espectrometría de Masas/métodos,
Transcriptoma/inmunología,
Análisis de Secuencia de ARN/instrumentación,
Coronavirus/patogenicidad,
Cromosomas/metabolismo,
Células Asesinas Naturales/clasificación,
Enfermedades Respiratorias/patología,
d0188440,
d0123130,
ddcs0500220,
d0454730,
d0127200
myrsine coriacea (Sw.) R. Br. ex Roem. & Schult. (Primulaceae) conhecida popularmente como capororoquinha ou capororoca, é amplamente distribuída nas regiões sul e sudeste do Brasil. As espécies desse gênero apresentam um potencial antioxidante e anti-inflamatório, que pode ser acessado na busca de...
Primulaceae/metabolismo,
Antioxidantes/análisis,
d0008930,
ddcs0518190,
d0642090,
Cromatografía en Capa Delgada/métodos,
Espectrometría de Masas/métodos,
Frutas/clasificación,
Hipopigmentación/patología,
Monofenol Monooxigenasa/análisis,
Myrsine/clasificación,
d0087220,
Pigmentación de la Piel/inmunología
Abstract The present study was aimed at conducting phytochemical analysis and evaluating the in vitro antifungal and antioxidant activities of the essential oil obtained from the fruits of J. oxycedrus L. Hydro-distillation was used to extract the essential oil from the fruits of Juniper oxycedrus. The ...
Antioxidantes/farmacología,
Aceites Volátiles/análisis,
Juniperus/efectos adversos,
Marruecos/etnología,
Frutas/clasificación,
Antifúngicos/farmacología,
Fitoquímicos/análisis,
Cromatografía de Gases/métodos,
Espectrometría de Masas/métodos,
d0000772220,
Pruebas de Sensibilidad Microbiana/métodos,
Técnicas In Vitro/métodos
Abstract Infusion solutions must be stable from the production stage until the infusion stage. Some infusion fluids contain degradation products, known as advanced glycation end products (AGEs); however, it is unknown whether AGEs exist in parenteral nutrition solutions. We aimed to investigate this ques...
Abstract Pterocarpus santalinoides is used in Nigerian ethnomedicine to treat diabetes mellitus. This study aimed to establish the antidiabetic property of the plant, and isolate and characterize its active principle. Dried and pulverized leaves (500 g) of P. santalinoides were extracted with 1.8 L of 80...
Extractos Vegetales/análisis,
Pterocarpus/efectos adversos,
Hipoglucemiantes/análisis,
Diabetes Mellitus/patología,
Acetatos/farmacología,
Cromatografía en Capa Delgada/métodos,
Espectrometría de Masas/métodos,
Espectroscopía de Resonancia Magnética/métodos,
Flavonoides/farmacología,
d0017860,
d0070040
Abstract The anecdotal use of Alternanthera sessilis L. as a relief for diabetes has been known in the Philippines for generations, and antidiabetic activity of similar varieties in other countries is likewise documented. However, the compounds responsible for this activity remain unclear. This study aim...
