BACKGROUND: Spermatogonial stem cells (SSCs) are critical for sustaining spermatogenesis. Even though several regulators of SSC have been identified in rodents, the regulatory mechanism of SSC in humans has yet to be discovered. METHODS: To explore the regulatory mechanisms of human SSCs, we analyzed pub...
ABSTRACT Introduction Chronic hyperglycemia is caused by diabetes mellitus-committed genital morphophysiology, and oxidative stress is one of the main factors involved in this process. Alpha lipoic acid (ALA) can prevent metabolic and morphological changes in diabetic individuals. Objectives In prese...
Antioxidantes/farmacología,
Diabetes Mellitus Experimental/patología,
Diabetes Mellitus Experimental/fisiopatología,
Epidídimo/efectos de los fármacos,
Epidídimo/patología,
Inmunohistoquímica,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Células de Sertoli,
Recuento de Espermatozoides,
Motilidad Espermática/efectos de los fármacos,
Espermatogénesis/efectos de los fármacos,
Espermatogénesis/fisiología,
Espermatozoides/efectos de los fármacos,
Espermatozoides/fisiología,
Testículo/efectos de los fármacos,
Testículo/patología,
Testículo/fisiopatología,
Ácido Tióctico/farmacología
BACKGROUND: Sperm production is one of the most complex biological processes in the body. In vitro production of sperm is one of the most important goals of researches in the field of male infertility treatment, which is very important in male cancer patients treated with gonadotoxic methods and drugs. I...
Abstract Purpose: To quantify, through stereological and morphometric analysis, spermatogenesis in rats undergoing the natural aging process. Methods: Seventy-two male Wistar rats were divided into 6 equal groups according to age at the time of killing: 3, 6, 9, 12, 18, and 24 months. All the rats were...
ABSTRACT Purpose To assess the impact of sperm retrieval on the gonadal function of rats with impaired spermatogenesis by comparing testicular sperm extraction (TESE) to aspiration (TESA). The efficacy of these procedures to sperm obtainment was also compared. Materials and Methods A pilot study showed...
Modelos Animales,
Orquidopexia/métodos,
Proyectos Piloto,
Distribución Aleatoria,
Ratas Wistar,
Motilidad Espermática/fisiología,
Recuperación de la Esperma/efectos adversos,
Espermatogénesis/fisiología,
Espermatozoides/fisiología,
Testículo/fisiología,
Testículo/cirugía,
Testosterona/biosíntesis
BACKGROUND: Chemokine (C-C motif) receptor 6 (CCR6) is present in sperm and plays a significant role in sperm motility and chemotaxis acting in the reproductive tracts. However, the expression and functional significance of CCR6 in testis are still poorly understood, especially in the process of spermato...
Quimiocina CCL20/metabolismo,
Quimiotaxis/fisiología,
Receptores CCR6/metabolismo,
Espermatogénesis/fisiología,
Criptorquidismo/metabolismo,
Motilidad Espermática/fisiología,
Testículo/fisiología,
Western Blotting,
Técnica del Anticuerpo Fluorescente,
Inmunohistoquímica,
Ratones Endogámicos C57BL,
Células de Sertoli
Abstract:The tropical gar A. tropicus plays an important ecological role as it regulates other fish stocks in different water bodies in Southeastern México. Nevertheless, wild populations are declining, and one conservation alternative is the aquaculture production and basic knowledge of reproductive bi...
Epitelio/fisiología,
Peces/fisiología,
México,
Valores de Referencia,
Reproducción/fisiología,
Estaciones del Año,
Maduración Sexual/fisiología,
Espermatogénesis/fisiología,
Espermatogonias/fisiología,
Testículo/anatomía & histología,
Testículo/fisiología,
Factores de Tiempo
AbstractThe golden mussel Limnoperna fortunei is an invasive species that has quickly dispersed and colonized several potential different habitats distributed all over the world, causing environmental and economic impacts. Thus, in order to contribute to a better understanding of the reproductive aspects...
BACKGROUND: Extracellular metolloproteases have been implied in different process such as cell death, differentiation and migration. Membrane-bound metalloproteases of the ADAM family shed the extracellular domain of many cytokines and receptor controlling auto and para/juxtacrine cell signaling in diffe...
Proteínas ADAM/metabolismo,
Espermatogénesis/fisiología,
Espermatozoides/metabolismo,
Proteínas ADAM/análisis,
Apoptosis/fisiología,
Diferenciación Celular/fisiología,
ARN Mensajero/análisis,
Túbulos Seminíferos/química,
Células de Sertoli/citología,
Células de Sertoli/metabolismo,
Espermátides/citología,
Espermátides/metabolismo,
Testículo/anatomía & histología,
Receptor fas/análisis,
Proteína ADAM10,
Proteína ADAM17,
Inmunohistoquímica,
Ratas Sprague-Dawley,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
