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Morphometrical analysis of the effect of nicotine administration on brain's prefrontal region in male rat

Int. j. morphol; 32 (3), 2014
Nicotine is the most important alkaloid compound in tobacco. One of the major effects of nicotine is stimulation of mesocorticolimbic system. Prefrontal cortex plays a pivotal role in personality and mental state. It is considered the main cause of addiction as it is located in mesocorticolimbic dopamine...