Higher body mass index and anti-drug antibodies predict the discontinuation of anti-TNF agents in Korean patients with axial spondyloarthritis
Rev. bras. reumatol; 57 (4), 2017
ABSTRACT Objective: The development of anti-drug antibodies against tumor necrosis factor inhibitors is a likely explanation for the failure of TNF-inhibitors in patients with spondyloarthritis. Our study determined the existence and clinical implications of ADAbs in axial spondyloarthritis patients. M...
Adalimumab/sangre, Adalimumab/inmunología, Antirreumáticos/sangre, Antirreumáticos/inmunología, Índice de Masa Corporal, Infliximab/sangre, Infliximab/inmunología, Modelos Logísticos, Persona de Mediana Edad, República de Corea, Espondiloartritis/sangre, Espondiloartritis/tratamiento farmacológico, Factor de Necrosis Tumoral alfa/antagonistas & inhibidores