Pre-diabetes induces ultrastructural alterations in the large blood vessel aorta in rats
Int. j. morphol; 37 (2), 2019
Excessive consumption of carbohydrate and fat increases the risk of cardiovascular disease. We sought to determine the potential ultrastructural alterations in large blood vessels induced by a high fat and fructose diet (HFD) in a rat model of prediabetes. Rats were either fed with HFD (model group) or a...
Estado Prediabético/patología, Estado Prediabético/metabolismo, Aorta Torácica/patología, Aorta Torácica/ultraestructura, Modelos Animales de Enfermedad, Lesiones del Sistema Vascular/patología, Lesiones del Sistema Vascular/etiología, Microscopía Electrónica de Transmisión, Grasas de la Dieta/efectos adversos, Fructosa, Aorta/patología, Aorta/ultraestructura, Ratas Sprague-Dawley