Therapeutic response and survival time of immunobiologicals in patients with moderate to severe psoriasis
An. bras. dermatol; 97 (1), 2022
Results: 28
Etanercept-induced palisaded neutrophilic granulomatous dermatitis
An. bras. dermatol; 96 (1), 2021
Informe diário de evidências COVID-19: busca realizada em 17 de julho de 2020
COVID-19 daily evidence report: search conducted on July 17, 2020
O Informe Diário de Evidências é uma produção do Ministério da Saúde que tem como objetivo acompanhar diariamente as publicações científicas sobre tratamento farmacológico e vacinas para a COVID-19. Dessa forma, são realizadas buscas estruturadas em bases de dados biomédicas, referentes ao d...
Infecciones por Coronavirus/tratamiento farmacológico, Neumonía Viral/tratamiento farmacológico, Betacoronavirus/efectos de los fármacos, Hidroxicloroquina/uso terapéutico, Azitromicina/uso terapéutico, Lopinavir/uso terapéutico, Ritonavir/uso terapéutico, Corticoesteroides/uso terapéutico, Darunavir/uso terapéutico, Cobicistat/uso terapéutico, Interferón beta-1a/uso terapéutico, Ganciclovir/uso terapéutico, Oseltamivir/uso terapéutico, Meropenem/uso terapéutico, Linezolid/uso terapéutico, Ribavirina/uso terapéutico, Dexametasona/uso terapéutico, Vancomicina/uso terapéutico, Cefepima/uso terapéutico, Antagonistas de Receptores Adrenérgicos beta 1/uso terapéutico, Inhibidores de la Enzima Convertidora de Angiotensina/uso terapéutico, Adalimumab/uso terapéutico, Etanercept/uso terapéutico, Abatacept/uso terapéutico, Estudios de Cohortes, Evaluación de la Tecnología Biomédica
Evaluation of the effect of intraperitoneal etanercept administration on oxidative stress and inflammation indicators in the kidney and blood of experimental sepsis-induced rats
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract INTRODUCTION: Sepsis is an important cause of mortality and morbidity, and inflammatory response and oxidative stress play major roles underlying its pathophysiology. Here, we evaluated the effect of intraperitoneal etanercept administration on oxidative stress and inflammation indicators in t...
Antiinflamatorios no Esteroideos/administración & dosificación, Antiinflamatorios no Esteroideos/farmacología, Modelos Animales de Enfermedad, Etanercept/administración & dosificación, Etanercept/farmacología, Inflamación/patología, Inflamación/prevención & control, Inyecciones Intraperitoneales, Riñón/efectos de los fármacos, Estrés Oxidativo/efectos de los fármacos, Ratas Sprague-Dawley, Sepsis/sangre, Sepsis/patología, Factor de Necrosis Tumoral alfa/sangre
Safety and tolerability of a single dose T0001 in Chinese healthy adult volunteers: a first-in-human ascending dose study
Braz. J. Pharm. Sci. (Online); 56 (), 2020
T0001 is the first mutant of etanercept with a higher affinity to tumor necrosis factor α (TNF-α) than etanercept. In order to investigate the safety and tolerability of T0001, a study was carried out in healthy Chinese subjects. A first-in-human, dose escalation study was conducted in healthy Chinese ...
Seguridad, Dosis Única/efectos de los fármacos, Etanercept/análogos & derivados, Factor de Necrosis Tumoral alfa/clasificación, Artritis Reumatoide/patología, Electrocardiografía, Examen Físico, Pueblo Asiatico/clasificación, Inyecciones Subcutáneas/clasificación, Reacción en el Punto de Inyección, Técnicas de Laboratorio Clínico, Voluntarios
Cardiac autonomic modulation in juvenile idiopathic arthritis with use of biological medication: relato de caso
Rev. bras. crescimento desenvolv. hum; 30 (1), 2020
INTRODUCTION: The introduction of biological medication in Juvenile Idiopathic Arthritis (JIA) proposes better therapeutic results with decreased pain and inflammation and consequent reduction in joint damage. The autonomic state can be a predictor for verifying the response to immunomodulation therapy. ...
Latent tuberculosis infection in patients with autoimmune diseases treated with Infliximab and Etanercept
Infectio; 23 (4), 2019
Introduction: Latent tuberculosis infection (LTI) in patients receiving biological therapies is a reality, but this has not been studied in depth in Colombia. Objective: To determine the prevalence of LTI in patients with autoimmune diseases receiving treatment with Infliximab / Etanercept in a referr...
Psoriasis in moderate grave plaque - immunobiological treatment
Rev. Assoc. Med. Bras. (1992, Impr.); 65 (4), 2019
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize producers to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the phy...
Anticuerpos Monoclonales/administración & dosificación, Anticuerpos Monoclonales/efectos adversos, Brasil, Toma de Decisiones Clínicas, Etanercept/administración & dosificación, Etanercept/efectos adversos, Factores Inmunológicos/administración & dosificación, Factores Inmunológicos/efectos adversos, Psoriasis/tratamiento farmacológico, Psoriasis/patología, Índice de Severidad de la Enfermedad, Factores de Tiempo, Resultado del Tratamiento, Factores de Riesgo
Correlation of ultrasonography synovitis with disease activity and clinical response to etanercept treatment in juvenile idiopathic arthritis patients
Braz. j. med. biol. res; 52 (12), 2019
This study aimed to investigate the correlation of ultrasonography (US) of synovitis with disease activity and clinical response to etanercept (ETN) in juvenile idiopathic arthritis (JIA) patients. Eighty-two JIA patients who underwent ETN treatment for 24 weeks were consecutively enrolled. US evaluation...
Perfil de gastos com o tratamento da Artrite Reumatoide para pacientes do Sistema Único de Saúde em Minas Gerais, Brasil, de 2008 a 2013
Ciênc. Saúde Colet. (Impr.); 23 (4), 2018
Resumo A artrite reumatoide (AR) é uma doença crônica que afeta cerca de 1% da população adulta. No estudo de coorte histórica de pacientes de Minas Gerais, registrados no Sistema de Informações Ambulatoriais (SIA), em 2008-2013, foram identificados 11.573 indivíduos. A perspectiva foi a do fina...
Antirreumáticos/administración & dosificación, Antirreumáticos/economía, Artritis Reumatoide/economía, Artritis Reumatoide/terapia, Brasil, Estudios de Cohortes, Etanercept/administración & dosificación, Etanercept/economía, Gastos en Salud, Persona de Mediana Edad, Programas Nacionales de Salud/economía, Análisis de Regresión, Factor de Necrosis Tumoral alfa/antagonistas & inhibidores