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The effect of intermittent fasting diet on the hippocampus of adult male mouse after inducing demyelination by ethidium bromide injection

Hassanpour, Azam; Hassanpour, Ashraf; Rezvani, Mohammad Ebrahim; Hosseini-Sharifabad, Mohamad; Basiri, Mohsen.
Int. j. morphol; 37 (3), 2019
Intermittent fasting diet (IF) as a restrictive regimen prevents neural degeneration and stimulates overexpression of various neurotropic factors in the hippocampus of animal models. This study evaluates the potential effect of the IF in the prevention of learning and memory dysfunction and improving the...
Enfermedades Desmielinizantes/inducido químicamente, Etidio/toxicidad, Hipocampo/patología, Ayuno, Ratones Endogámicos BALB C, Modelos Animales de Enfermedad, Peso Corporal, Aprendizaje
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Propentofylline reduces glial scar development following gliotoxic damage in the rat brainstem

Bondan, Eduardo Fernandes; Martins, Maria de Fátima Monteiro; Dossa, Pietro Domingues; Viebig, Lígia Bocamino; Cardoso, Carolina Vieira; Martins Júnior, João Lopes; Bernardi, Maria Martha.
Arq. neuropsiquiatr; 74 (9), 2016
ABSTRACT Propentofylline is a xanthine derivative that depresses activation of glial cells, whose responses contribute to neural tissue damage during inflammation. Ethidium bromide injection into the central nervous system induces local oligodendroglial and astrocytic loss, resulting in primary demyelina...
Astrocitos/efectos de los fármacos, Astrocitos/metabolismo, Tronco Encefálico/efectos de los fármacos, Tronco Encefálico/metabolismo, Enfermedades Desmielinizantes/metabolismo, Enfermedades Desmielinizantes/prevención & control, Modelos Animales de Enfermedad, Etidio/toxicidad, Proteína Ácida Fibrilar de la Glía/análisis, Proteína Ácida Fibrilar de la Glía/efectos de los fármacos, Gliotoxina/toxicidad, Inmunohistoquímica, Fármacos Neuroprotectores/farmacología, Ratas Wistar, Reproducibilidad de los Resultados, Factores de Tiempo, Resultado del Tratamiento, Xantinas/farmacología
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