Abnormal expression of TBX4 during anorectal development in rat embryos with ethylenethiourea-induced anorectal malformations
Biol. Res; 52 (), 2019
BACKGROUND: To assess the expression of T-box transcription factor 4 (TBX4) during the anorectal development in normal and ethylenethiourea (ETU)-induced anorectal malformations (ARM) rat embryos. METHODS: Anorectal malformations was induced by ETU on the 10th gestational day (E10) in rat embryos. Spati...
Malformaciones Anorrectales/genética, Etilenotiourea/farmacología, Regulación de la Expresión Génica/genética, Proteínas de Dominio T Box/genética, Malformaciones Anorrectales/inducido químicamente, Western Blotting, Inmunohistoquímica, Ratas Wistar, Reacción en Cadena en Tiempo Real de la Polimerasa, Proteínas de Dominio T Box/metabolismo