LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

The role of ischemic preconditioning in gene expression related to inflammation in a rat model of intestinal ischemia-reperfusion injury

Miranda, Celina Teresa Castelo Branco Couto de; Fagundes, Djalma José; Miranda, Edinaldo de; Simões, Ricardo Santos; Taha, Murched Omar.

Acta cir. bras; 33 (12), 2018

Abstract Purpose: To investigate the gene expression related to inflammation on mice subjected to intestinal ischemia and reperfusion (I/R) and treated with ischemic preconditioning (IPC). Methods: Thirty rats (EPM-Wistar), distributed in five groups of six animals each, were underwent anesthesia and...

Regulación hacia Abajo/fisiología, Expresión Génica/fisiología, Inflamación/genética, Inflamación/prevención & control, Intestino Delgado/irrigación sanguínea, Precondicionamiento Isquémico/métodos, Isquemia Mesentérica/genética, Isquemia Mesentérica/prevención & control, Ratas Wistar, Reacción en Cadena en Tiempo Real de la Polimerasa, Valores de Referencia, Daño por Reperfusión/genética, Daño por Reperfusión/prevención & control, Reproducibilidad de los Resultados, Factores de Tiempo, Resultado del Tratamiento, Regulación hacia Arriba/fisiología

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MicroRNA-122 regulates caspase-8 and promotes the apoptosis of mouse cardiomyocytes

Zhang, ZW; Li, H; Chen, SS; Li, Y; Cui, ZY; Ma, J.

Braz. j. med. biol. res; 50 (2), 2017

Cardiomyocyte apoptosis plays key roles in the pathogenesis of heart diseases such as myocardial infarction. MicroRNAs are important regulators of gene expression, which are also involved in the regulation of cardiomyocyte apoptosis. However, cardiomyocyte apoptosis regulated by microRNA (miR)-122 is lar...

Animales Recién Nacidos, Apoptosis/genética, Caspasa 8/genética, Expresión Génica/genética, Expresión Génica/fisiología, Ratones Endogámicos BALB C, MicroARNs/genética, MicroARNs/fisiología, Miocitos Cardíacos/patología

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The antioxidative defense system is involved in the premature senescence in transgenic tobacco (Nicotiana tabacum NC89)

Liu, Yu; Wang, Lu; Liu, Heng; Zhao, Rongrong; Liu, Bin; Fu, Quanjuan; Zhang, Yuanhu.

Biol. Res; 49 (), 2016

BACKGROUND: α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. white winterpearmain), and transformed into tobacco (Nicotiana tabacum NC89). Th...

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