Guimarães, Keyth Sulamitta de Lima;
Toscano, Luciana Tavares;
Costa, Bagnólia Araújo;
Souza, Iara Leão Luna de;
Polari, Isabelle de Lima Brito;
Wanderley, Ivyne Oliveira Araújo;
Miranda Neto, Manoel;
Barros, Bárbara Cavalcanti;
Queiroz, Rubens Teixeira de;
Cordeiro, Ângela Maria Tribuzy de Magalhães;
Gonçalves, Maria da Conceição Rodrigues;
Toscano, Lydiane de Lima Tavares;
Silva, Alexandre Sérgio.
Abstract We investigated the vasodilatory effects of Hymenaea rubriflora Ducke stem bark extract (HRHAc). Vascular reactivity of the aortic rings of Wistar rats was tested by in vitro cumulative doses (0.1 - 729 μg/mL). Rats (n=5) were treated with 25 (G25), 50 (G50) and 100 (G100) mg/ kg of HR-HAc or s...
Oliveira, Leilanne Márcia Nogueira de;
Bastos, Maria do Socorro Rocha;
Lima, Ana Cristina Silva de;
Figueiredo, Evânia Altina Teixera de;
Dias, Flayanna Gouveia Braga;
Silva, Larissa Morais Ribeiro da;
Benevides, Selene Dahia;
Ribeiro, Paulo Riceli Vasconcelos;
Sabino, Luiz Bruno de Sousa;
Figueiredo, Raimundo Wilane de.
Abstract In this research, aqueous and ethanolic extracts from Justicia pectoralis Jacq and Croton Jacobinensis Baill were characterized. The UPLC-QTOF-MSE analysis was performed on the extracts identified, predominantly, flavonoids, tannins and acids. The extracts did not indicate toxicity in human epit...
ABSTRACT Diabetes is a life-threatening disease, and currently available synthetic medicines for treating diabetes are associated with various side effects. Therefore, there is an unmet need to develop herbal remedies against diabetes as an alternative to synthetic medicines. Although local healers use t...
Abstract Present study analysed the therapeutic potential of traditionally acclaimed medicinal herb Nanorrhinum ramosissimum, using plant parts extracted with different solvents (10 mg/mL). Shoot extracts exhibited comparatively better antimicrobial properties, in comparison to root extracts. Total pheno...
Abstract Guarana (Paullinia cupana) is a native plant from the Amazon whose seeds contain a high concentration of caffeine. Aqueous extract of guarana is widely used in the world. In this study, the objective was to develop and validate a High-Performance Liquid Chromatography method for the determinatio...
Abstract Pterocarpus santalinoides is used in Nigerian ethnomedicine to treat diabetes mellitus. This study aimed to establish the antidiabetic property of the plant, and isolate and characterize its active principle. Dried and pulverized leaves (500 g) of P. santalinoides were extracted with 1.8 L of 80...
Extractos Vegetales/análisis,
Pterocarpus/efectos adversos,
Hipoglucemiantes/análisis,
Diabetes Mellitus/patología,
Acetatos/farmacología,
Cromatografía en Capa Delgada/métodos,
Espectrometría de Masas/métodos,
Espectroscopía de Resonancia Magnética/métodos,
Flavonoides/farmacología,
d0017860,
d0070040
Abstract The phenolic compound content, the antioxidant and α-amylase inhibition potentials of different extracts of the Plectranthus amboinicus, P. barbatus and P. ornatus were evaluated. We also evaluated the influence of plant growth and harvest time on the chemical composition of the essential oil ...
Abstract The aim of this work is to study three cultivars of artichoke (Cynara cardunculus var. scolymus): Gauchito, Guri and Oro Verde in terms of their in vitro chemoprevention and anti-inflammatory properties. These cultivars show good productive performance. The phenolic composition of their fresh le...
Abstract Some plants of the genus Pulicaria have been used in traditional medicines for treating back pain and inflammation. They possess various bioactivities such as antipyretic, analgesic, and hepatoprotective. This study aimed to investigate the potential analgesic, antipyretic, anti- inflammatory, a...
Abstract Degenerative diseases diabetes and oxidative stress constitute a major health concern worldwide. Medicinal plants are expected to provide effective and affordable remedies. The present research explored antidiabetic and antioxidant potential of extracts of Carissa opaca roots. Methanolic extract...