de Oliveira, Gustavo Rezende Bellei;
Rocha, Fabíola Dutra;
Nunomura, Rita de Cássia Saraiva;
Roberto, João Paulo;
Merino, Francis José Zortéa;
de Oliveira, Vinícius Bednarczuk;
Rech, Katlin Suellen;
Alves, Emellie Cristine;
Furusho, Aletheia dos Santos;
Montrucchio, Deise Prehs;
Dias, Josiane de Fátima Gaspari;
Valdameri, Glaucio;
Zanzarini, Isadora da Silva;
Miguel, Obdulio Gomes;
Miguel, Marilis Dallarmi.
Trunk barks of Sacoglottis ceratocarpa Ducke (ScTB) are used in Amazonian folk medicine against hyperglycemia and dyslipidemia, although scientific information on efficacy and quality control is lacking. Thus, pharmacognostic parameters, qualitative phytochemical profile, antioxidant pr...
Antioxidantes/química,
Antioxidantes/farmacología,
Extractos Vegetales/química,
Medicina Tradicional,
Magnoliopsida/química,
Extractos Vegetales/farmacología,
Farmacognosia,
Flavonoides/análisis,
Fenoles/análisis,
Difracción de Rayos X,
Benzopiranos/análisis,
Ácido Gálico/análisis,
Antioxidantes/toxicidad,
Extractos Vegetales/toxicidad,
Fitoquímicos
dos Santos, Jymmys Lopes;
Silva, Ana Mara de Oliveira e;
Souza, Lúcio Marques Vieira;
Pereira, Raquel Oliveira;
Lima, Clésio Andrade;
Abreu, Lucas Silva;
Montalvao, Monalisa Martins;
Correa, Cristiane Bani;
Rabelo, Thallita Kelly;
Duarte, Marcelo Cavalcante;
Aidar, Felipe Jose;
Tavares, Josean Fechine;
Estevam, Charles dos Santos;
Marçal, Anderson Carlos.
In order to understand antidiabetic potential and toxicity, this study aimed to evaluate the acute toxicity and antidiabetic activity of ethanolic extract and ethyl acetate fraction obtained from Coutoubea spicata “nicolau” shoots. Chemical constituents and acute toxicity were investigated. In alloxa...
Extractos Vegetales/química,
Extractos Vegetales/toxicidad,
Extractos Vegetales/farmacología,
Etanol,
Diabetes Mellitus/tratamiento farmacológico,
Gentianaceae/química,
Hiperglucemia/tratamiento farmacológico,
Hipoglucemiantes/química,
Hipoglucemiantes/farmacología,
Cromatografía Líquida de Alta Presión,
Flavonoides/análisis,
Fenoles/análisis,
Supervivencia Celular,
Ratas Wistar,
Peso Corporal/efectos de los fármacos,
Oxidación-Reducción/efectos de los fármacos,
Hipoglucemiantes/toxicidad
Abstract Origanum vulgare has been of great interest in academia and pharma industry due to its antioxidant, antifungal and antitumor properties. The present study aimed to find the anti-MRSA potential and in vivo toxicity assessments of O. vulgare. O. vulgare extract was used to monitor anti-MRSA activi...
Leaf and fruit decoctions of Schinus areira L. from northwest Argentina were investigated here. Phenolic compounds and organic acids were analyzed by HPLC. Antioxidant capacity and α-glucosidase inhibition were determined by using in vitro tests. The general toxicity was assessed against Artemia salina...
Abstract Aims: To identify the histopathological alterations in organs of Wistar rats to evaluate toxic effects of use of Annonamuricata Raw Leaf Extract (AMRLE) alone or in association with DMBA. Settings and Design: Sixty female Wistar rats were used, separated into groups and treated with a single dos...
Nematicidal substances have been identified from plants and are potentially useful for the management of plant-parasitic nematodes. Cabralea canjerana, (Meliaceae) and Schinus terebinthifolius (Anacardiaceae) produce bioactive compounds during their secondary metabolism and little is known about the effe...
Plants that produce secondary metabolites with allelopathic activity or phytotoxicity can be biotechnologically important, serving as sources of allelochemicals, and thus contributing to the agroindustrial sector. Vismia japurensis (Hypericaceae) is an Amazonian species that grows in clumps called vismia...
Abstract Vernonanthura polyanthes, popularly known as assa-peixe, is a medicinal plant that has been widely used by Brazilian Cerrado population for treatment of diseases without a detailed evaluation of their effectiveness, toxicity, and proper dosage. Thus, more studies investigating the safety of V. p...
Figueiredo Júnior, Ernani Canuto;
Cavalcanti, Yuri Wanderley;
Lira, Andressa Brito;
Pessoa, Hilzeth de Luna Freire;
Lopes, Wilton Silva;
da Silva, Diego Romário;
Freires, Irlan Almeida;
Rosalen, Pedro Luiz;
Costa, Edja Maria Melo de Brito;
Pereira, Jozinete Vieira.
This study determined phytochemical composition, antifungal activity and toxicity in vitro and in vivo of Syzygium cumini leaves extract (Sc). Thus, was characterized by gas chromatography coupled to mass spectrometry and submitted to determination of Minimum Inhibitory (MIC) and Fungicidal concentrati...
Syzygium/química,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/toxicidad,
Antifúngicos/química,
Antifúngicos/farmacología,
Antifúngicos/toxicidad,
Hojas de la Planta/química,
Pruebas de Sensibilidad Microbiana,
Candida/efectos de los fármacos,
Pruebas de Toxicidad,
Cromatografía de Gases y Espectrometría de Masas,
Antioxidantes,
Compuestos Fenólicos/análisis
Gatto, Larissa Junqueira;
Oliveira, Gustavo Rezende Bellei de;
Rech, Katlin Suellen;
Moura, Paula Francislaine;
Gribner, Caroline;
Merino, Francis José Zortéa;
Ávila, Suelen;
Dias, Josiane de Fatima Gaspari;
Miguel, Obdulio Gomes;
Miguel, Marilis Dallarmi.
Several species of the Myrcia genus have been used in folk medicine to treat diabetes. Therefore, the aim of this work was to investigate the inhibitory activity of α-glucosidase and pancreatic lipase in the crude extract (EBF) and in the ethyl acetate fraction (FFA) of Myrcia hatschbachii, as well as t...
Myrtaceae/química,
Antioxidantes/farmacología,
Inhibidores de Glicósido Hidrolasas/farmacología,
Lipasa/efectos de los fármacos,
Páncreas/enzimología,
Extractos Vegetales/farmacología,
Extractos Vegetales/toxicidad,
Ácido Gálico,
Ácido Elágico,
Extractos Vegetales/química,
Antioxidantes/química,
Fenoles/análisis,
Difracción de Rayos X,
Depuradores de Radicales Libres,
Técnicas In Vitro,
Mezclas Complejas
