REC8 suppresses tumor angiogenesis by inhibition of NF-κB-mediated vascular endothelial growth factor expression in gastric cancer cells
Biol. Res; 53 (), 2020
BACKGROUND: Tumor angiogenesis is an essential event for tumor growth and metastasis. It has been showed that REC8, a component of the meiotic cohesion complex, played a vital role in Epithelial-Mesenchymal Transition (EMT) in gastric cancer. However, the role of REC8 in gastric cancer angiogenesis remai...
Proteínas de Ciclo Celular/genética, FN-kappa B/genética, Neovascularización Patológica/genética, Neoplasias Gástricas/patología, Factor A de Crecimiento Endotelial Vascular/genética, Neoplasias Gástricas/irrigación sanguínea, Línea Celular Tumoral, Células Endoteliales de la Vena Umbilical Humana, Microambiente Tumoral