LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

EIF1AX c.338-2A>T splice site mutation in a patient with trabecular adenoma and cytological indeterminate lesion

Castagna, Maria Grazia; Pilli, Tania; Maino, Fabio; Marzocchi, Carlotta; Cairano, Giovanni Di; Cantara, Silvia.

Arch. endocrinol. metab. (Online); 64 (2), 2020

SUMMARY The EIF1AX gene mutations have been recently associated with papillary thyroid carcinoma and anaplastic thyroid cancer. According with these reports, the gene as been considered as a drive gene for thyroid cancer development. However, the occurrence of these alterations in benign thyroid lesions ...

Adenoma/diagnóstico, Adenoma/genética, Biopsia con Aguja Fina, Factor 1 Eucariótico de Iniciación/genética, Persona de Mediana Edad, Mutación/genética, Neoplasias de la Tiroides/diagnóstico, Neoplasias de la Tiroides/genética

Fulltext

Evaluation of Reference Genes for Quantitative PCR in Four Tissues from Rabbits with Hypercholesterolaemia

Abstract Rabbit with hypercholesterolaemia is an important model for studying cholesterol metabolism disease. This study aimed to evaluate the expression stability of nine reference genes for quantitative PCR (qPCR) analysis in adrenal gland, liver, spleen, and kidney tissue from rabbits with hypercholes...