Granulocyte colony-stimulating factor combined with Methylprednisolone improves functional outcomes in rats with experimental acute spinal cord injury
Clinics; 73 (), 2018
OBJECTIVES: To evaluate the effects of combined treatment with granulocyte colony-stimulating factor (G-CSF) and methylprednisolone in rats subjected to experimental spinal cord injury. METHODS: Forty Wistar rats received a moderate spinal cord injury and were divided into four groups: control (no treat...
Modelos Animales de Enfermedad, Combinación de Medicamentos, Factor Estimulante de Colonias de Granulocitos/farmacocinética, Metilprednisolona/farmacocinética, Fármacos Neuroprotectores/farmacocinética, Distribución Aleatoria, Ratas Wistar, Recuperación de la Función/efectos de los fármacos, Valores de Referencia, Reproducibilidad de los Resultados, Traumatismos de la Médula Espinal/tratamiento farmacológico, Traumatismos de la Médula Espinal/patología, Traumatismos de la Médula Espinal/rehabilitación, Factores de Tiempo, Resultado del Tratamiento