LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Expression of AIF, PARP, and miRNAs MIR-145, MIR-210, and MIR-486 associated with apoptosis in the corpus cavernosum of rats subjected to chronic alcoholism model

Int. j. morphol; 38 (6), 2020

SUMMARY: Previous studies from our group described the consequences of using ethanol on penile erection. Nevertheless, the molecular mechanisms surrounding microRNAs, apoptosis process and their relationship with erectile dysfunction associated with alcohol consumption are still poorly understood. The ob...

Alcoholismo/metabolismo, Disfunción Eréctil/metabolismo, Apoptosis, MicroARNs/metabolismo, Factor Inductor de la Apoptosis/metabolismo, Pene/química, Modelos Animales de Enfermedad, Inmunohistoquímica, Ratas Wistar, MicroARNs/análisis, Factor Inductor de la Apoptosis/análisis, Alcoholismo/fisiopatología, Disfunción Eréctil/fisiopatología, Pene/fisiopatología, Reacción en Cadena en Tiempo Real de la Polimerasa, MicroARNs/genética, Factor Inductor de la Apoptosis/genética

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AIF, PARP-1 and MicroRNA-9 expression in cerebral ischemia associated to alcoholism experimental model

Abrahão, Dayana Pousa Siqueira; Lizarte Neto, Fermino Sanches; Rodrigues, Andressa Romualdo; Cirino, Múcio Luiz de Assis; Silva, Jairo Pinheiro da; Sarraipo, Vagner Schiavoni; Carvalho, Camila Albuquerque Melo de; Tazima, Maria de Fátima Galli Sorita; Carlotti-Jr, Carlos Gilberto; Colli, Benedicto Oscar; Tirapelli, Luís Fernando; Tirapelli, Daniela Pretti da Cunha.

Int. j. morphol; 38 (3), 2020

The chronic consumption of alcohol causes a worsening of the events that follow the cerebral ischemia. These events are regulated through the expression of several genes and microRNAs. The aimof this work was To analyze and describe the expression profile of PARP and AIF and miRNA-9 proteins in rats subm...

Alcoholismo/metabolismo, Alcoholismo/genética, Isquemia Encefálica/metabolismo, Isquemia Encefálica/genética, Modelos Animales de Enfermedad, Factor Inductor de la Apoptosis/metabolismo, Poli(ADP-Ribosa) Polimerasa-1/metabolismo, Inmunohistoquímica, Ratas Wistar, MicroARNs/metabolismo

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Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes

Liu, Guo; Zhang, Wenhao.

Braz. j. med. biol. res; 51 (8), 2018

Excessive exposure to ultraviolet (UV) rays can cause damage of the skin and may induce cancer, immunosuppression, photoaging, and inflammation. The long non-coding RNA (lncRNA) HOX antisense intergenic RNA (HOTAIR) is involved in multiple human biological processes. However, its role in UVB-induced kera...

Apoptosis/fisiología, Apoptosis/efectos de la radiación, Factor Inductor de la Apoptosis/metabolismo, Supervivencia Celular/fisiología, Expresión Génica, Inflamación/etiología, Interleucina-6/metabolismo, Queratinocitos/metabolismo, Queratinocitos/efectos de la radiación, FN-kappa B/efectos de los fármacos, FN-kappa B/metabolismo, Fosfatidilinositol 3-Quinasas/metabolismo, ARN Largo no Codificante/metabolismo, Factor de Necrosis Tumoral alfa/metabolismo, Rayos Ultravioleta/efectos adversos, Regulación hacia Arriba, eIF-2 Quinasa/metabolismo

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