A doença de Still do adulto é uma rara condição inflamatória, cujo
diagnóstico é um desafio, por se tratar de diagnóstico de exclusão, após vasta investigação. Manifesta-se com febre alta diária,
amigdalite não supurativa, artrite, rash evanescente, leucocitose e
hiperferritinemia. O pre...
Enfermedad de Still del Adulto/diagnóstico,
Diagnóstico Diferencial,
Infecciones/diagnóstico,
Neoplasias/diagnóstico,
Enfermedades Reumáticas/diagnóstico,
Enfermedades Raras/diagnóstico,
Fiebre,
Artralgia,
Exantema,
Leucocitosis/sangre,
Faringitis,
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Factor Reumatoide/sangre,
Enfermedad de Still del Adulto/tratamiento farmacológico,
Corticoesteroides/uso terapéutico,
Antirreumáticos/uso terapéutico,
Hiperferritinemia/sangre,
Proteína C-Reactiva/análisis,
Sedimentación Sanguínea,
Esplenomegalia
Rheumatoid arthritis is a clinical autoimmune syndrome that causes joint damage. The positive or negative anti-cyclic citrullinated protein (CCP) antibodies serodiagnosis differentiates two subsets of the disease, each with different genetic background. Previous studies have identified associations betwe...
Abstract Rheumatoid arthritis (RA) is an autoimmune/inflammatory disease affecting 0.5 to 1% of adults worldwide and frequently leads to joint destruction and disability. Early diagnosis and early and effective therapy may prevent joint damage and lead to better long-term results. Therefore, reliable bio...
Abstract Introduction: Rheumatoid arthritis (RA) is a well-documented independent risk factor for cardiovascular disease. Obesity may provide an additional link between inflammation and accelerated atherosclerosis in RA. Objective: To evaluate the association between obesity and disease parameters and ...
Artritis Reumatoide/epidemiología,
Obesidad/epidemiología,
Adipoquinas/metabolismo,
Factores de Edad,
Análisis de Varianza,
Artritis ReumatoideSangre,
Aterosclerosis/epidemiología,
Índice de Masa Corporal,
Brasil/epidemiología,
Estudios Transversales,
Diabetes Mellitus Tipo 2/epidemiología,
DislipidemiasSangre,
Dislipidemias/epidemiología,
Hipertensión/epidemiología,
Modelos Logísticos,
ObesidadSangre,
Obesidad/diagnóstico,
Sobrepeso/diagnóstico,
Sobrepeso/epidemiología,
Prevalencia,
Factor ReumatoideSangre,
Factores de Riesgo
ABSTRACT Objectives: To evaluate the frequency of four serum biomarkers in RA patients and their relatives and identify possible associations with clinical findings of the disease. Methods: This was a transversal analytical study. Anti-cyclic citrullinated peptide (anti-CCP), anti-mutated citrullinated...
Anticuerpos Antiproteína Citrulinada/sangre,
Artralgia/etiología,
Artritis Reumatoide/sangre,
Artritis Reumatoide/clasificación,
Artritis Reumatoide/complicaciones,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Ensayo de Inmunoadsorción Enzimática,
Persona de Mediana Edad,
Factor Reumatoide/sangre,
Vimentina/sangre
ABSTRACT Objective: The aim of this study was to assess the relationship between the two types of posttranslational modifications of proteins in RA: glycosylation on the example of carbohydrate-deficient transferrin and citrullination by means of autoantibodies to cyclic citrullinated peptides. Methods...
Anticuerpos Antiproteína Citrulinada/sangre,
Artritis Reumatoide/inmunología,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Citrulinación,
Glicosilación,
Persona de Mediana Edad,
Péptidos Cíclicos/inmunología,
Factor Reumatoide/sangre,
Índice de Severidad de la Enfermedad,
Transferrina/análogos & derivados,
Transferrina/metabolismo
ABSTRACT Purpose: We aimed to compare the retinal nerve fiber layer, ganglion cell layer, inner plexiform layer, and the choroid thickness between patients with Behcet disease and healthy subjects by using spectral domain optical coherence tomography (SD-OCT). Methods: Ninety eyes of 45 healthy subject...
ABSTRACT Introduction: The presence of anti-CCP is an important prognostic tool of rheumatoid arthritis (RA). But research is still ongoing on its relationship with disease activity and functional capacity. Objectives: To study the relationship between anti-CCP and disease activity, functional capacity...
Artritis Reumatoide/sangre,
Artritis Reumatoide/diagnóstico por imagen,
Artritis Reumatoide/inmunología,
Artritis Reumatoide/fisiopatología,
Autoanticuerpos/sangre,
Autoanticuerpos/inmunología,
Biomarcadores/sangre,
Estudios Transversales,
Imagen por Resonancia Magnética,
Persona de Mediana Edad,
Péptidos Cíclicos/sangre,
Péptidos Cíclicos/inmunología,
Valor Predictivo de las Pruebas,
Pronóstico,
Factor Reumatoide/sangre,
Índice de Severidad de la Enfermedad
Resumo Objetivo: Caracterizar pacientes com artrite reumatoide (AR) quanto à presença de fatores de risco para doenças cardiovasculares. Material e métodos: Estudo transversal descritivo com 71 pacientes diagnosticados com AR definida. Foram usados os instrumentos: DAS-28, HAQ e SF-36 e determinados ...
Anticuerpos Antiproteína Citrulinada/sangre,
Artritis Reumatoide/sangre,
Artritis Reumatoide/complicaciones,
Glucemia/análisis,
Sedimentación Sanguínea,
Brasil,
Enfermedades Cardiovasculares/sangre,
Enfermedades Cardiovasculares/etiología,
Colesterol/sangre,
Estudios Transversales,
Persona de Mediana Edad,
Factor Reumatoide/sangre,
Factores de Riesgo
