Results: 3

Extract of Ascaris suum induces TGF-β and early production of IgG1 in experimental autoimmune hepatitis

Abstract In experimental autoimmune hepatitis (EAH) of Th1 profile, an extract of adult Ascaris suum worms (ASC) was previously found to deviate the immune response to a Th2/IL-10 pattern. Here, the effects of treatment with ASC on production of TGF-β and the anti-Ascaris isotypes IgG1 and IgG2a in ...

6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression

An. acad. bras. ciênc; 89 (4), 2017
ABSTRACT 6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice were treated with saline, or different concentr...

Oral or topical administration of L-arginine changes the expression of TGF and iNOS and results in early wounds healing

Acta cir. bras; 31 (9), 2016
ABSTRACT PURPOSE: To evaluate the contribution of L-arginine oral or topical rout of administration in the surgical wound healing process. METHODS: L-arginine was orally or topically administrated to mice after a laparotomy model procedure. The wounds were analyzed to evaluate the granulation tissue by...