Resumo Objetivo investigar a associação entre a frequência de eventos estressores e citocinas em pessoas idosas longevas. Métodos os participantes responderam a um questionário constituído de variáveis sociodemográficas, indicaram quais eventos estressores constantes no Inventário de...
Abstract Objectives This study aimed to explore the effect of antidepressant treatment on the HPA axis, changes in depression score, and serum levels of TNF-α in depressed infertile women. Methods In this randomized controlled trial research, 60 infertile women who had undergone in vitro fertiliza...
Depresión/tratamiento farmacológico,
Infertilidad Femenina/psicología,
Sistema Hipotálamo-Hipofisario/efectos de los fármacos,
Factor de Necrosis Tumoral alfa/sangre,
Fertilización In Vitro,
Fluoxetina/uso terapéutico,
Resultado del Tratamiento,
Hidrocortisona/sangre,
Infertilidad Femenina/terapia,
Antidepresivos/uso terapéutico,
Factor de Necrosis Tumoral alfa/efectos de los fármacos
ABSTRACT Objective The aim of this study was to investigate polycystic ovary syndrome (PCOS) and to explore the relationship between body fat percentage and metabolic markers. Subjects and methods Sedentary women were assigned to PCOS (N = 60) and CONTROL (N = 60) groups. Each group was subdivided in...
17-alfa-Hidroxiprogesterona/sangre,
Adiponectina/sangre,
Tejido Adiposo/anatomía & histología,
Andrógenos/sangre,
Biomarcadores/sangre,
Índice de Masa Corporal,
Estudios de Casos y Controles,
Hormona Folículo Estimulante/sangre,
Glucosa/análisis,
Insulina/sangre,
Resistencia a la Insulina,
Interleucina-6/sangre,
Leptina/sangre,
Hormona Luteinizante/sangre,
Enfermedades Metabólicas/sangre,
Factor de Necrosis Tumoral alfa/sangre
Rheumatoid arthritis (RA) is an autoimmune disease of knee joints involving pain and inflammation. Rhoifolin is a plant flavonoid known to have antioxidant and anti-inflammatory properties. This study was taken to identify the effect of rhoifolin on complete Freund's adjuvant (CFA)-induced arthritis in t...
Artritis Experimental/tratamiento farmacológico,
Artritis Experimental/metabolismo,
Artritis Reumatoide/tratamiento farmacológico,
Artritis Reumatoide/metabolismo,
Biomarcadores/sangre,
Citocinas/sangre,
Disacáridos/administración & dosificación,
Flavonoides/administración & dosificación,
Adyuvante de Freund/administración & dosificación,
Glicósidos/administración & dosificación,
Interleucina-1beta/sangre,
Interleucina-6/sangre,
FN-kappa B/efectos de los fármacos,
FN-kappa B/metabolismo,
Estrés Oxidativo/efectos de los fármacos,
Factor de Necrosis Tumoral alfa/sangre
Aydın, Emre;
Yıldırım, Yaşar;
Aydin, Fatma Yilmaz;
Bahadir, Mehmet Veysi;
Kaplan, Ibrahim;
Kadiroğlu, Berfin;
Ketani, Muzaffer Aydin;
Yilmaz, Zülfükar;
Kadiroğlu, Ali Kemal;
Yilmaz, Mehmet Emin.
Abstract INTRODUCTION: Sepsis is an important cause of mortality and morbidity, and inflammatory response and oxidative stress play major roles underlying its pathophysiology. Here, we evaluated the effect of intraperitoneal etanercept administration on oxidative stress and inflammation indicators in t...
Antiinflamatorios no Esteroideos/administración & dosificación,
Antiinflamatorios no Esteroideos/farmacología,
Modelos Animales de Enfermedad,
Etanercept/administración & dosificación,
Etanercept/farmacología,
Inflamación/patología,
Inflamación/prevención & control,
Inyecciones Intraperitoneales,
Riñón/efectos de los fármacos,
Estrés Oxidativo/efectos de los fármacos,
Ratas Sprague-Dawley,
Sepsis/sangre,
Sepsis/patología,
Factor de Necrosis Tumoral alfa/sangre
Abstract Background Inflammation is involved in the pathophysiology of depression, and circulating inflammatory cytokines have been associated with depressive symptoms. However, measuring circulating cytokines have inherent methodological limitations. In vitro lipopolysaccharide (LPS)-stimulated intrac...
Citocinas/sangre,
Lipopolisacáridos,
Depresión/fisiopatología,
Estudios Transversales,
Inflamación/fisiopatología,
Biomarcadores/sangre,
Monocitos/metabolismo,
Escalas de Valoración Psiquiátrica,
Interleucina-6/sangre,
Proteína C-Reactiva,
Factor de Necrosis Tumoral alfa/sangre,
Técnicas In Vitro,
Depresión/sangre,
Inflamación/sangre
SUMMARY OBJECTIVE The aim of this study was to determine the potential association of foot pain and plasmatic adipocytes as physiological biomarkers of childhood obesity with the incidence of flatfoot in a cohort of Egyptian school children aged 6 -12 years. METHODS A total of 550 Egyptian schoolchil...
Adipocitos/química,
Adiponectina/sangre,
Biomarcadores/sangre,
Índice de Masa Corporal,
Estudios de Cohortes,
Estudios Transversales,
Ensayo de Inmunoadsorción Enzimática,
Pie Plano/sangre,
Pie Plano/complicaciones,
Interleucina-6/sangre,
Leptina/sangre,
Obesidad/sangre,
Obesidad/complicaciones,
Dolor/sangre,
Dolor/etiología,
Dimensión del Dolor,
Resistina/sangre,
Índice de Severidad de la Enfermedad,
Factor de Necrosis Tumoral alfa/sangre
ABSTRACT Fatigue is one of the most frequent and disabling symptoms in multiple sclerosis (MS). Central, psychological, and peripheral factors may contribute to the occurrence of fatigue. Objectives: The current study aimed to evaluate potential fatigue determinants in patients with relapsing-remitting ...
Evaluación de la Discapacidad,
Fatiga/complicaciones,
Fatiga/fisiopatología,
Interleucina-6/sangre,
Presiones Respiratorias Máximas,
Esclerosis Múltiple Recurrente-Remitente/complicaciones,
Esclerosis Múltiple Recurrente-Remitente/fisiopatología,
Análisis Multivariante,
Fatiga Muscular/fisiología,
Escalas de Valoración Psiquiátrica,
Calidad de Vida,
Respiración,
Índice de Severidad de la Enfermedad,
Estadísticas no Paramétricas,
Factor de Necrosis Tumoral alfa/sangre
SUMMARY BACKGROUND: There is no strong evidence on the link between inflammatory profile and pattern of drug treatment response in depressive patients that could result in Coronary Artery Disease occurrence. OBJECTIVE: This study aimed to compare the subclinical atherosclerosis markers, inflammatory pr...
Antiinflamatorios/uso terapéutico,
Antidepresivos/uso terapéutico,
Aterosclerosis/sangre,
Biomarcadores/sangre,
Trastorno Bipolar/sangre,
Trastorno Bipolar/diagnóstico,
Trastorno Bipolar/tratamiento farmacológico,
Índice de Masa Corporal,
Factor Neurotrófico Derivado del Encéfalo/sangre,
Trastorno Depresivo Resistente al Tratamiento/sangre,
Trastorno Depresivo Resistente al Tratamiento/diagnóstico,
Trastorno Depresivo Resistente al Tratamiento/tratamiento farmacológico,
Interleucina-1beta/sangre,
Interleucina-6/sangre,
Modelos Logísticos,
Persona de Mediana Edad,
Valor Predictivo de las Pruebas,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Estadísticas no Paramétricas,
Factor de Necrosis Tumoral alfa/sangre
ABSTRACT Objective: The aim of this study was to evaluate the relationship between inflammatory cytokines, placental weight, glycated hemoglobin and adverse perinatal outcomes (APOs) in women with gestational diabetes mellitus (GDM). Subjects and methods: This was a prospective, longitudinal and observ...
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Diabetes Gestacional/sangre,
Hemoglobina Glucada/análisis,
Interleucina-6/sangre,
Estudios Longitudinales,
Placenta/patología,
Valor Predictivo de las Pruebas,
Resultado del Embarazo,
Estudios Prospectivos,
Factor de Necrosis Tumoral alfa/sangre
