LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

IRF6 polymorphisms in Brazilian patients with non-syndromic cleft lip with or without palate

Bezerra, João Felipe; Silva, Heglayne Pereira Vital da; Bortolin, Raul Hernandes; Luchessi, André Ducati; Ururahy, Marcela Abbott Galvão; Loureiro, Melina Bezerra; Gil-da-Silva-Lopes, Vera Lúcia; Almeida, Maria das Graças; Amaral, Viviane Souza do; Rezende, Adriana Augusto de.

Braz. j. otorhinolaryngol. (Impr.); 86 (6), 2020

Abstract Introduction: Non-syndromic orofacial clefts have a complex etiology due to the contribution from both genetic and environmental risk factors, as well as the interaction between them. Among the more than 15 susceptibility loci for non-syndromic orofacial clefts with considerable statistical and...

Brasil, Labio Leporino/genética, Fisura del Paladar/genética, Predisposición Genética a la Enfermedad, Genotipo, Factores Reguladores del Interferón/genética, Polimorfismo Genético

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IRF6 rs2235375 single nucleotide polymorphism is associated with isolated non-syndromic cleft palate but not with cleft lip with or without palate in South Indian population

Gurramkonda, Venkatesh Babu; Syed, Altaf Hussain; Murthy, Jyotsna; Lakkakula, Bhaskar V K S.

Braz. j. otorhinolaryngol. (Impr.); 84 (4), 2018

Abstract Introduction Transcription factors are very diverse family of proteins involved in activating or repressing the transcription of a gene at a given time. Several studies using animal models demonstrated the role of transcription factor genes in craniofacial development. Objective We aimed to in...

Estudios de Casos y Controles, Labio Leporino/etnología, Labio Leporino/genética, Fisura del Paladar/etnología, Fisura del Paladar/genética, Frecuencia de los Genes, Estudios de Asociación Genética, Técnicas de Genotipaje, India, Factores Reguladores del Interferón/genética, Polimorfismo de Nucleótido Simple/genética, Factores de Riesgo

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Association of single nucleotide polymorphisms in AXIN2, BMP4, and IRF6 with Non-Syndromic Cleft Lip with or without Cleft Palate in a sample of the southeast Iranian population

Rafighdoost, Houshang; Hashemi, Mohammad; Danesh, Hiva; Bizhani, Fatemeh; Bahari, Gholamreza; Taheri, Mohsen.

J. appl. oral sci; 25 (6), 2017

Abstract Non-syndromic cleft lip with or without palate (NSCL/P) is a common congenital malformation worldwide, with complex etiology. It has been proposed that interaction of genes and environmental factors play a role in the predisposition to this disease. Objectives: The aim of this study was to exam...

Proteína Axina/genética, Proteína Morfogenética Ósea 4/genética, Estudios de Casos y Controles, Labio Leporino/genética, Fisura del Paladar/genética, Frecuencia de los Genes, Predisposición Genética a la Enfermedad, Genotipo, Factores Reguladores del Interferón/genética, Irán, Polimorfismo de Longitud del Fragmento de Restricción, Polimorfismo de Nucleótido Simple

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