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Effect of Physical Training on Nitric Oxide Levels in Patients with Arterial Hypertension: An Integrative Review

Facioli, Tábata de Paula; Buranello, Mariana Colombini; Regueiro, Eloisa Maria Gatti; Basso-Vanelli, Renata Pedrolongo; Durand, Marina de Toledo.
Int. j. cardiovasc. sci. (Impr.); 35 (2), 2022
Abstract The regular practice of physical exercise as a non-pharmacological treatment of arterial hypertension (AH) has been encouraged due to causing a series of physiological responses in the cardiovascular system, such as the production of vasoactive substances, including nitric oxide (NO). NO is a re...
Óxido Nítrico/metabolismo, Factores Relajantes Endotelio-Dependientes/metabolismo, Ejercicio Físico/fisiología, Acondicionamiento Físico Humano/fisiología, Hipertensión/terapia, Presión Arterial/fisiología, Hipertensión/metabolismo
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Pharmacological characterization of the calcium influx pathways involved in nitric oxide production by endothelial cells

Silva, Janyerson Dannys Pereira da; Ballejo, Gustavo.
Einstein (Säo Paulo); 17 (3), 2019
ABSTRACT Objective: To characterize the calcium influx pathways implicated in the sustained elevation of endothelial intracellular calcium concentration, required for the synthesis and release of relaxing factors. Methods: We evaluated the effect of the newly synthesized pyrazole derivatives, described...
Acetilcolina/farmacología, Aorta Torácica/efectos de los fármacos, Calcio/farmacología, Canales de Calcio Activados por la Liberación de Calcio/metabolismo, Células Endoteliales/efectos de los fármacos, Células Endoteliales/metabolismo, Factores Relajantes Endotelio-Dependientes/metabolismo, Óxido Nítrico/metabolismo, Ratas Wistar, Canales Catiónicos TRPC/metabolismo, Canales Catiónicos TRPV/efectos de los fármacos, Canales Catiónicos TRPV/metabolismo, Tapsigargina/farmacología, Factores de Tiempo, Vasodilatadores/farmacología
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Effects of a Single Bout of Resistance Exercise in Different Volumes on Endothelium Adaptations in Healthy Animals

Mota, Marcelo Mendonça; Silva, Tharciano Luiz Teixeira Braga da; Macedo, Fabricio Nunes; Mesquita, Thássio Ricardo Ribeiro; Quintans Júnior, Lucindo José; Santana-Filho, Valter Joviniano de; Lauton-Santos, Sandra; Santos, Márcio Roberto Viana.
Arq. bras. cardiol; 108 (5), 2017
Abstract Background: Resistance exercise (RE) has been recommended for patients with cardiovascular diseases. Recently, a few studies have demonstrated that the intensity of a single bout of RE has an effect on endothelial adaptations to exercise. However, there is no data about the effects of different...
Endotelio Vascular/efectos de los fármacos, Endotelio Vascular/fisiología, Factores Relajantes Endotelio-Dependientes/fisiología, Inhibidores Enzimáticos/farmacología, Insulina/farmacología, Arterias Mesentéricas/efectos de los fármacos, Arterias Mesentéricas/fisiología, NG-Nitroarginina Metil Éster/farmacología, Óxido Nítrico/fisiología, Condicionamiento Físico Animal/fisiología, Distribución Aleatoria, Ratas Wistar, Entrenamiento de Fuerza, Vasodilatación/efectos de los fármacos, Vasodilatadores/farmacología
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The effect of chronic nitric oxide inhibition on vascular reactivity and blood pressure in pregnant rats

Takiuti, Nilton Hideto; Carvalho, Maria Helena Cetelli; Kahhale, Soubhi; Nigro, Dorothy; Barbeiro, Hermes Vieira; Zugaib, Marcelo.
Säo Paulo med. j; 117 (5), 1999
CONTEXT: The exact mechanism involved in changes in blood pressure and peripheral vascular resistance during pregnancy is unknown. OBJECTIVE:To evaluate the importance of endothelium-derivated relaxing factor (EDRF) and its main component, nitric oxide, in blood pressure and vascular reactivity in pregna...
Óxido Nítrico/antagonistas & inhibidores, Factores Relajantes Endotelio-Dependientes/antagonistas & inhibidores, NG-Nitroarginina Metil Éster/farmacología, Inhibidores Enzimáticos/farmacología, Acetilcolina/farmacología, Vasodilatadores/farmacología, Aorta/efectos de los fármacos, Vasodilatación/efectos de los fármacos, Presión Sanguínea, Ratas Wistar
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