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Effect of Physical Training on Nitric Oxide Levels in Patients with Arterial Hypertension: An Integrative Review

Facioli, Tábata de Paula; Buranello, Mariana Colombini; Regueiro, Eloisa Maria Gatti; Basso-Vanelli, Renata Pedrolongo; Durand, Marina de Toledo.
Int. j. cardiovasc. sci. (Impr.); 35 (2), 2022
Abstract The regular practice of physical exercise as a non-pharmacological treatment of arterial hypertension (AH) has been encouraged due to causing a series of physiological responses in the cardiovascular system, such as the production of vasoactive substances, including nitric oxide (NO). NO is a re...
Óxido Nítrico/metabolismo, Factores Relajantes Endotelio-Dependientes/metabolismo, Ejercicio Físico/fisiología, Acondicionamiento Físico Humano/fisiología, Hipertensión/terapia, Presión Arterial/fisiología, Hipertensión/metabolismo
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Pharmacological characterization of the calcium influx pathways involved in nitric oxide production by endothelial cells

Silva, Janyerson Dannys Pereira da; Ballejo, Gustavo.
Einstein (Säo Paulo); 17 (3), 2019
ABSTRACT Objective: To characterize the calcium influx pathways implicated in the sustained elevation of endothelial intracellular calcium concentration, required for the synthesis and release of relaxing factors. Methods: We evaluated the effect of the newly synthesized pyrazole derivatives, described...
Acetilcolina/farmacología, Aorta Torácica/efectos de los fármacos, Calcio/farmacología, Canales de Calcio Activados por la Liberación de Calcio/metabolismo, Células Endoteliales/efectos de los fármacos, Células Endoteliales/metabolismo, Factores Relajantes Endotelio-Dependientes/metabolismo, Óxido Nítrico/metabolismo, Ratas Wistar, Canales Catiónicos TRPC/metabolismo, Canales Catiónicos TRPV/efectos de los fármacos, Canales Catiónicos TRPV/metabolismo, Tapsigargina/farmacología, Factores de Tiempo, Vasodilatadores/farmacología
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