Stem cells are undifferentiated cells that can be distinguished from others by their ability to self-renew and to differentiate into new specific cell types. Mesenchymal stem cells (MSC) are adult stem cells that can be obtained from different sources, such as adipose tissue, bone marrow, dental pulp, an...
Biomarcadores/análisis,
Células Madre Mesenquimatosas/clasificación,
Proteína ADAM17/farmacología,
Adipocitos/metabolismo,
Antígenos/efectos adversos,
Estratos Germinativos,
Citocinas/efectos adversos,
Citometría de Flujo/instrumentación,
Coloración y Etiquetado/métodos,
Condrocitos/clasificación,
Células Madre,
Cordón Umbilical,
Células Madre Adultas/clasificación,
ADN/agonistas,
Espectrometría de Masas/métodos,
Factores de Crecimiento Transformadores/agonistas,
Fibroblastos/química,
Aislamiento de Pacientes,
Scientists for Health and Research for Development,
Separación Celular/instrumentación,
Trasplante/efectos adversos,
Técnica SELEX de Producción de Aptámeros/instrumentación
As Células-Tronco Mesenquimais (CTMs), são células multipotentes, presentes em diversos tecidos, sendo bastante estudada devido sua capacidade imunorregulatória por meio da liberação de fatores solúveis. Fatores estes que atuam sobre as funções de células do sistema imunitário. Simultaneamente...
SUMMARY: Diabetes is a metabolic disorder characterized by high blood sugar levels and it causes complications in many systems, including the reproductive system. As a result of diabetic conditions, one of the mechanisms that can cause repression of reproductive activity is testicular oxidant stress. The...
ABSTRACT Objective: To compare Transforming growth factor-β1 (TGF-β1) expression in various L-PRF concentrations on the hDPSC differentiation process. Material and Methods: hDPSC cell cultures were subjected to serum starvation by reducing FBS levels in the hDPSC culture media. Lysate PRF was...
Na presença de Diabetes Mellitus, a doença periodontal (DP) pode acentuar o aparecimento de complicações e aumentar sua prevalência. O objetivo desta pesquisa foi avaliar se o Fator de Crescimento Transformador -β do tipo 1 (TGFβ1, sigla em inglês) e Metaloproteinase de matriz -9 (MMP-9, sigla em...
Colágeno,
Colágeno Tipo I,
Diabetes Mellitus,
Enfermedades Periodontales,
Factores de Crecimiento Transformadores,
Fibroblastos,
Encía,
Metaloproteinasas de la Matriz,
Diabetes Mellitus/epidemiología,
Inhibidores de la Metaloproteinasa de la Matriz,
Dexametasona
Resumen Introducción: la enfermedad de hígado graso no alcohólico (NAFLD) constituye un problema de salud pública asociado con el síndrome metabólico; su patogénesis implica el inicio de una cascada de señalización bioquímica compleja y su estimulación continua podría consolidar un proceso d...
ABSTRACT Background: Rheumatoid arthritis is a widely prevalent autoimmune disorder with suggested genetic predisposition. Objectives: The aim of this study is to detect the pattern of genetic polymorphism of methylene tetrahydrofolate reductase (MTHFR C677 T and A1298 C), transforming growth factor-&#...
ABSTRACT Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants used in traditional medicine for the treatment of inflammatory diseases and other ailments. Objective In this study, we evaluated whether budlein A modulates the activation of innate and adaptive immune c...
Análisis de Varianza,
Antiinflamatorios/farmacología,
Apoptosis/efectos de los fármacos,
Asteraceae/química,
Proliferación Celular/efectos de los fármacos,
Células Cultivadas,
Ensayo de Inmunoadsorción Enzimática,
Citometría de Flujo,
Interleucina-8/análisis,
Interleucina-8/efectos de los fármacos,
Interleucinas/análisis,
Lactonas/farmacología,
Neutrófilos/efectos de los fármacos,
Peroxidasa/análisis,
Peroxidasa/efectos de los fármacos,
Reproducibilidad de los Resultados,
Sesquiterpenos/farmacología,
Linfocitos T/efectos de los fármacos,
Factores de Crecimiento Transformadores/análisis,
Factores de Crecimiento Transformadores/efectos de los fármacos
Visentainer, Jeane E. L;
Lieber, Sofia R;
Persoli, Ligia B. L;
Marques, Silvia B. D;
Vigorito, Afonso C;
Aranha, Francisco J. P;
Eid, Katia A. B;
Oliveira, Gislaine B;
Miranda, Eliana C. M;
Souza, Cármino A. de.
Several candidate gene studies have demonstrated that genetic polymorphisms in cytokine genes contribute to variations in the levels of cytokines produced and this variation may influence the occurrence and severity of complications after stem cell transplantation (HSCT). In this work we compared the ser...
Enfermedad Injerto contra Huésped,
Trasplante de Médula Ósea,
Trasplante de Células Madre,
Trasplante de Células Madre Hematopoyéticas,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético,
Interleucina-10,
Interleucina-6,
Genotipo,
Factores de Crecimiento Transformadores,
Ensayo de Inmunoadsorción Enzimática,
Citocinas,
Donantes de Tejidos
