Rehman, S U;
Muhammad, K;
Novaes, E;
Que, Y;
Din, A;
Islam, M;
Porto, A C M;
Sajid, M;
Ullah, N;
Iqsa, S.
Abstract Transcription factors (TF) are a wide class of genes in plants, and these can regulate the expression of other genes in response to various environmental stresses (biotic and abiotic). In the current study, transcription factor activity in sugarcane was examined during cold stress. Initially, RN...
BACKGROUND: Knowledge about regulating transcription factors (TFs) for osteoblastogenesis from mesenchymal stem cells (MSCs) is limited. Therefore, we investigated the relationship between genomic regions subject to DNA-methylation changes during osteoblastogenesis and the TFs known to directly interact ...
Durante a carcinogênese oral, as células malignas adquirem um fenótipo agressivo que resulta em aumento da motilidade individual e na capacidade para invadir tecidos circunvizinhos. Para tanto, as células epiteliais malignas desenvolvem um processo regulatório e programado denominado transição epi...
Abstract Introduction: Non-syndromic cleft lip with or without cleft palate is a common worldwide birth defect due to a combination of environmental and genetic factors. Genome-wide association studies reported the rs7078160 of Vax1 is closely related to non-syndromic cleft lip with or without cleft pal...
Alsagaby, Suliman A;
Brewis, Ian A;
Vijayakumar, Rajendran;
Alhumaydhi, Fahad A;
Alwashmi, Ameen S;
Alharbi, Naif K;
Al Abdulmonem, Waleed;
Premanathan, Mariappan;
Pratti, Guy;
Fegan, Christopher;
Pepper, Christopher;
Brennan, Paul.
BACKGROUND: Chronic lymphocytic leukaemia (CLL) is a neoplasm of B-cells characterized by variable prognosis. Exploring the proteome of CLL cells may provide insights into the disease. Therefore, eleven proteomics experiments were conducted on eleven primary CLL samples. RESULTS: We reported a CLL proteo...
O melanoma é um tipo de câncer de pele geneticamente diverso, que surge diante das transformações em melanócitos. A mutação BRAFV600E está presente em mais de 90% de todas as mutações em BRAF, sendo assim ocorre em cerca de 50% dos casos registrados. As mutações em NRAS, ocupam o segundo luga...
Citoplasma/clasificación,
Asociación,
Fosfotransferasas/antagonistas & inhibidores,
Factores de Transcripción/agonistas,
Genoma,
Melanoma,
Melanocitos/clasificación,
Migración Humana,
Neoplasias/patología,
Piel/lesiones,
Receptores de Hidrocarburo de Aril
Current understanding of the genetic factors contributing to the etiology of non-syndromic craniosynostosis (NSC) remains scarce. The present work investigated the presence of variants in ALX4, EFNA4, and TWIST1 genes in children with NSC to verify if variants within these genes may contribute to the occ...
BACKGROUND: Cichoric acid (CA) is extracted from Echinacea purpurea. It is well known and widely used for its immunological function. However, the effect of CA on peripheral blood mononuclear cells (PBMCs) from yaks is still unclear. This study investigated the potential influences of CA on the prolifera...
Echinacea/química,
Ácidos Cafeicos/farmacología,
Succinatos/farmacología,
Proliferación Celular/efectos de los fármacos,
Apoptosis/efectos de los fármacos,
Factores de Transcripción,
Leucocitos Mononucleares/citología,
Leucocitos Mononucleares/efectos de los fármacos,
Ensayo de Inmunoadsorción Enzimática,
Western Blotting,
Reacción en Cadena en Tiempo Real de la Polimerasa,
RNA-Seq,
Citocinas,
Concanavalina A/farmacología
Abstract Instruction: Noise-induced hearing loss is a leading occupational disease caused by gene-environment interaction. The Grainy Like 2, GRHL2, is a candidate gene. In this regard, many studies have evaluated the association between GRHL2 and noise-induced hearing loss, although the results are amb...
