Results: 6

Expression analysis of transcription factors in sugarcane during cold stress

Rehman, S U; Muhammad, K; Novaes, E; Que, Y; Din, A; Islam, M; Porto, A C M; Sajid, M; Ullah, N; Iqsa, S.

Braz. j. biol; 83 (), 2023

Abstract Transcription factors (TF) are a wide class of genes in plants, and these can regulate the expression of other genes in response to various environmental stresses (biotic and abiotic). In the current study, transcription factor activity in sugarcane was examined during cold stress. Initially, RN...

Frío, Respuesta al Choque por Frío/genética, Perfilación de la Expresión Génica, Regulación de la Expresión Génica de las Plantas, Saccharum/genética, Saccharum/metabolismo, Estrés Fisiológico/genética, Factores de Transcripción/genética, Factores de Transcripción/metabolismo

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DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation

Gómez, Rodolfo; Barter, Matt J; Alonso-Pérez, Ana; Skelton, Andrew J; Proctor, Carole; Herrero-Beaumont, Gabriel; Young, David A.

Biol. Res; 56 (), 2023

BACKGROUND: Knowledge about regulating transcription factors (TFs) for osteoblastogenesis from mesenchymal stem cells (MSCs) is limited. Therefore, we investigated the relationship between genomic regions subject to DNA-methylation changes during osteoblastogenesis and the TFs known to directly interact ...

Células Madre Mesenquimatosas, Osteogénesis/genética, Diferenciación Celular/genética, Metilación de ADN, Factores de Transcripción/genética, Factores de Transcripción/metabolismo

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Expression and significance of CK5/6, P63, P40, CK7, TTF-1, NapsinA, CD56, Syn and CgA in biopsy specimen of squamous cell carcinoma, adenocarcinoma and small cell lung carcinoma

Wang, Jing-yuan; Wang, Xue-min; Xu, Xiao-yan; Li, Shi-rong; Liu, Xiu-lan.

Int. j. morphol; 38 (2), 2020

Nine tumor and various potential biomarkers were measured and combined the information to diagnose disease, all patients accepted fiber bronchoscopy brush liquid based cytologyand histopathology examination in order to reliably detect lung cancer. The samples from 314 Chinese lung cancer patients were ob...

Neoplasias Pulmonares/metabolismo, Neoplasias Pulmonares/patología, Carcinoma/metabolismo, Carcinoma/patología, Biomarcadores de Tumor/metabolismo, Carcinoma de Células Escamosas/metabolismo, Carcinoma de Células Escamosas/patología, Adenocarcinoma/metabolismo, Adenocarcinoma/patología, Carcinoma de Células Pequeñas/metabolismo, Carcinoma de Células Pequeñas/patología, Inmunohistoquímica, Sensibilidad y Especificidad, Queratinas Tipo II/metabolismo, Factores de Transcripción/metabolismo, Proteínas Supresoras de Tumor/metabolismo, Fragmentos de Péptidos/metabolismo, Queratina-7/metabolismo, Factor Nuclear Tiroideo 1/metabolismo, Ácido Aspártico Endopeptidasas/metabolismo, Antígeno CD56/metabolismo

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Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Zhu, Qing; Li, Jingchao; Wu, Qi; Cheng, Yongxia; Zheng, Huizhe; Zhan, Tao; Wang, Hongwei; Yang, Yue; Wang, Hongyan; Liu, Ye; Guo, Sufen.

Biol. Res; 53 (), 2020

BACKGROUND: LincRNAs have been revealed to be tightly associated with various tumorigeneses and cancer development, but the roles of specific lincRNA on tumor-related angiogenesis was hardly studied. Here, we aimed to investigate whether linc-OIP5 in breast cancer cells affects the angiogenesis of HUVECs...

Proteínas Adaptadoras Transductoras de Señales/metabolismo, Neoplasias de la Mama/patología, Células Endoteliales de la Vena Umbilical Humana/citología, Neuropilina-1/metabolismo, Receptores Notch/metabolismo, Factores de Transcripción/metabolismo, Microambiente Tumoral, Neoplasias de la Mama/metabolismo, Western Blotting, Línea Celular Tumoral, Inmunohistoquímica, Reacción en Cadena en Tiempo Real de la Polimerasa, Reacción en Cadena de la Polimerasa de Transcriptasa Inversa, Transducción de Señal

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Expression and purification of the transcription factor StMsn2 from Setosphaeria turcica in Escherichia coli

Lv, Runling; Liu, Yuwei; Gong, Xiaodong; Han, Jianmin; Gu, Shouqin; Dong, Jingao.

Electron. j. biotechnol; 40 (), 2019

Background: In Saccharomyces cerevisiae, Msn2, which acts as a key transcription factor downstream the MAPKHOG cascade pathway, also regulates the expression of genes related to stress responses. However, little is known about the regulation mechanisms of the transcription factor in Setosphaeria turcica....

Ascomicetos/genética, Ascomicetos/patogenicidad, Ascomicetos/metabolismo, Escherichia coli, Factores de Transcripción/aislamiento & purificación, Factores de Transcripción/genética, Factores de Transcripción/metabolismo, Helminthosporium, Enfermedades de las Plantas, Zea mays, Epítopos, Clonación Molecular, Expresión Génica, Sistemas de Lectura Abierta, Estrés Fisiológico, Dedos de Zinc, Western Blotting, Proteínas Portadoras

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Decreased expression of chromodomain helicase DNA-binding protein 9 is a novel independent prognostic biomarker for colorectal cancer

Xu, Li; Peng, Hui; Huang, Xiao-Xu; Xia, Ya-Bin; Hu, Kai-Feng; Zhang, Zheng-Ming.

Braz. j. med. biol. res; 51 (9), 2018

Previous studies suggested that chromodomain helicase DNA-binding proteins (CHDs), including CHD 1-8, were associated with several human diseases and cancers including lymphoma, liver cancer, colorectal cancer, stomach cancer, etc. To date, little research on CHD 9 in human cancers has been reported. In ...

Biomarcadores de Tumor/genética, Biomarcadores de Tumor/metabolismo, Neoplasias Colorrectales/genética, Neoplasias Colorrectales/metabolismo, Neoplasias Colorrectales/patología, ADN Helicasas, Proteínas de Unión al ADN/genética, Proteínas de Unión al ADN/metabolismo, Regulación Neoplásica de la Expresión Génica, Inmunohistoquímica, Estimación de Kaplan-Meier, Estadificación de Neoplasias, Pronóstico, Transactivadores, Factores de Transcripción/genética, Factores de Transcripción/metabolismo

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