Results: 3

Isolation of breast cancer stem cell from MDA-MB231 cell line using vincristine

Int. j. morphol; 34 (4), 2016
Cancer has been considered as a stem cell disease. Suspension culture combined with anti-cancer drugs has recently been proposed for isolation of cancer stem cells (CSCs). In the current study, Vincristine as an anti-cancer drug combined with suspension culture was used for isolation and purification of ...

Immunohistochemical analysis of retinoblastoma cell phenotype using neuronal and glial cell markers

Arq. bras. oftalmol; 79 (6), 2016
ABSTRACT Purpose: The cellular origin of retinoblastoma is uncertain as constituent tumor cells heterogeneously express markers of both immature and mature retinal cells. An immunohistochemical analysis of cellular origin may yield valuable insights into disease progression and treatment options. This s...

Sox2 function as a negative regulator to control HAMP expression

Biol. Res; 48 (), 2015
BACKGROUND: Hepcidin, encoding by HAMP gene, is the pivotal regulator of iron metabolism, controlling the systemic absorption and transportation of irons from intracellular stores. Abnormal levels of HAMP expression alter plasma iron parameters and lead to iron metabolism disorders. Therefore,itis animpo...