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The influence of dehydroepiandrosterone on effector functions of neutrophils

Brauer, Verônica Soares; Zambuzi, Fabiana Albani; Espíndola, Milena Sobral; Cavalcanti Neto, Marinaldo Pacífico; Prado, Morgana Kelly Borges; Cardoso, Priscilla Mariane; Soares, Luana Silva; Galvao-Lima, Leonardo Judson; Leopoldino, Andréia Machado; Cardoso, Cristina Ribeiro de Barros; Frantz, Fabiani Gai.
Braz. J. Pharm. Sci. (Online); 57 (), 2021
Dehydroepiandrosterone (DHEA) is a steroid hormone secreted by the adrenal glands, gonads and brain. It is a precursor to sex hormones and also is known to have immune modulatory activity. However, little is known about the relationship between DHEA and neutrophils and thus our study evaluates the influe...
Neutrófilos/metabolismo, Deshidroepiandrosterona/análisis, Fagocitosis/genética, Glándulas Suprarrenales/metabolismo, Hormonas Esteroides Gonadales/farmacología, Salmonella enterica/clasificación, Técnicas In Vitro
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Relationships between phagocytosis, mucoid phenotype, and genetic characteristics of Klebsiella pneumoniae clinical isolates

Cavalcanti, Francinete Carla Nunes; Rodrigues, Juliana Falcão; Cabral, Adriane Borges; Azarias, Larissa Caina Barbosa de; Morais Júnior, Marcos Antônio de; Castro, Célia Maria Machado Barbosa de; Lopes, Ana Catarina de Souza.
Rev. Soc. Bras. Med. Trop; 52 (), 2019
Abstract INTRODUCTION The relationships between phagocytosis, and mucoid phenotype, plasmid profile and virulence, and resistance genetic characteristics of Klebsiella pneumoniae clinical isolates were evaluated. METHODS Thirty isolates were used to determine the mucoid aspect. Four were selected for...
Antibacterianos/farmacología, Farmacorresistencia Microbiana/genética, Klebsiella pneumoniae/efectos de los fármacos, Klebsiella pneumoniae/genética, Klebsiella pneumoniae/patogenicidad, Fagocitosis/genética, Fagocitosis/fisiología, Fenotipo, Plásmidos, Virulencia/genética, Factores de Virulencia/genética
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