Inclusion complexes and self-assembled cyclodextrin aggregates for increasing the solubility of benzimidazoles
Braz. J. Pharm. Sci. (Online); 55 (), 2019
Albendazole and fenbendazole are imidazole derivatives that exhibit broad spectrum activity against parasites, but the low solubility of these drugs considerably reduces their effectiveness. Complexation of albendazole and fenbendazole with cyclodextrins (β-cyclodextrin and hydroxypropyl-β-cyclodextrin...