Abstract Introduction: Bone cancer metastasis may produce severe and refractory pain. It is often difficult to manage with systemic analgesics. Chemical neurolysis may be an effective alternative in terminally ill patients. Case report: Female terminally ill patient with hip metastasis of gastric cance...
Artralgia,
Analgésicos,
Dolor en Cáncer/tratamiento farmacológico,
Nervio Femoral,
Pacientes Internos,
Neoplasias,
Nervio Obturador,
Dolor Intratable/tratamiento farmacológico,
Dolor Intratable/etiología,
Fenol,
Fenoles/farmacología,
Ultrasonografía Intervencional
HIGHLIGHTS The phenolic composition, antioxidant activity and cytotoxic potential of the extracts of C. solstitialis and U. picroides were investigated. Caffeic acid was found as the most abundant phenolic compound in the extracts. Both species showed promising antioxidant activity towards different...
Antioxidantes/farmacología,
Asteraceae/química,
Centaurea/química,
Compuestos Fenólicos/análisis,
Ácidos Cafeicos/farmacología,
Fenoles/farmacología,
Extractos Vegetales/farmacología,
Cromatografía Líquida de Alta Presión,
Turquía,
Plantas Medicinales,
Citotoxinas/farmacología,
Células HEK293
Despite the development of modern medicine, alternative medicine, which has not lost its timeliness, remains attractive for the treatment of various diseases. Glabridin, a major flavonoid of Glycyrrhiza glabra, is known for its antioxidant and anti-inflammatory activity. The aim of this study was: 1) to...
Isoflavonas/administración & dosificación,
Isoflavonas/farmacología,
Fenoles/administración & dosificación,
Fenoles/farmacología,
Daño por Reperfusión/tratamiento farmacológico,
Íleon/efectos de los fármacos,
Estrés Oxidativo/efectos de los fármacos,
Músculo Liso/efectos de los fármacos,
NG-Nitroarginina Metil Éster,
AMP Cíclico/metabolismo,
GMP Cíclico/metabolismo,
Ratas Wistar,
Malondialdehído/análisis,
AMP Cíclico/análisis,
Íleon/química,
Glycyrrhiza
Manilkara zapota (Sapotaceae), commonly known as Sapodilla, is widely known for its delicious fruit. Various parts of this plant are also used in folk medicine to treat a number of conditions including fever, pain, diarrhoea, dysentery, haemorrhage and ulcers. Scientific studies have demonstrated analges...
Manilkara/química,
Sapotaceae/química,
Medicina Tradicional,
Compuestos Fenólicos/análisis,
Extractos Vegetales/farmacología,
Fenoles/aislamiento & purificación,
Fenoles/farmacología,
Carotenoides/aislamiento & purificación,
Carotenoides/farmacología,
Triterpenos/aislamiento & purificación,
Triterpenos/farmacología,
Saponinas/aislamiento & purificación,
Saponinas/farmacología,
Esteroles/aislamiento & purificación,
Esteroles/farmacología
ABSTRACT Lignocellulose-derived inhibitors have negative effects on the ethanol fermentation capacity of Saccharomyces cerevisiae. In this study, the effects of eight typical inhibitors, including weak acids, furans, and phenols, on glucose and xylose co-fermentation of the recombinant xylose-fermenting ...
Ácidos/metabolismo,
Ácidos/farmacología,
Fermentación,
Furanos/metabolismo,
Furanos/farmacología,
Glucosa/metabolismo,
Microbiología Industrial,
Fenoles/metabolismo,
Fenoles/farmacología,
Saccharomyces cerevisiae/efectos de los fármacos,
Saccharomyces cerevisiae/genética,
Saccharomyces cerevisiae/crecimiento & desarrollo,
Saccharomyces cerevisiae/metabolismo,
Xilosa/metabolismo
ABSTRACT Morus nigra L. (Moraceae) is a tree known as black mulberry and the leaves are used in folk medicine in the treatment of diabetes, high cholesterol and menopause symptoms. The aim of this study was to evaluate the M. nigra leaves phytochemical profile in different extractions and the hypolipidem...
Antioxidantes/farmacología,
Ácido Ascórbico/farmacología,
Modelos Animales de Enfermedad,
Flavonoides/farmacología,
Lípidos/sangre,
Morus/química,
Fenoles/aislamiento & purificación,
Fenoles/farmacología,
Extractos Vegetales/farmacología,
Hojas de la Planta/química,
Ratas Wistar
PAIVA, DERISVALDO R;
LIMA, DÊNIS P DE;
AVVARI, NAGA P;
ARRUDA, EDUARDO J DE;
CABRINI, ISAIAS;
MARQUES, MARIA RITA;
SANTOS, EDSON A DOS;
BIAGGIO, FRANCISCO C;
SANGI, DIEGO P;
BEATRIZ, ADILSON.
ABSTRACT Cardanol is a constituent of Cashew Nut Shell Liquid that presents larvicidal activity against Aedes aegypti. The isolation of cardanol is somewhat troublesome, however, in this work we describe an efficient and inexpensive method to obtain it as a pure material. The compound was used as startin...
Aedes/efectos de los fármacos,
Insecticidas/síntesis química,
Insecticidas/farmacología,
Insecticidas/toxicidad,
Larva/efectos de los fármacos,
Dosificación Letal Mediana,
Fenoles/química,
Fenoles/aislamiento & purificación,
Fenoles/farmacología,
Fenoles/toxicidad,
Factores de Tiempo
ABSTRACT Peel extracts of litchi and rambutan, and that of tamarind seed coat were investigated in relation to their utility in skin-aging treatments. Standardized extracts of tamarind were significantly (p < 0.05) more efficient at O2 •- scavenging (IC50 = 27.44 ± 0.09) than those of litchi an...
Administración Cutánea,
Antioxidantes/aislamiento & purificación,
Antioxidantes/farmacología,
Cosméticos,
Fibroblastos/efectos de los fármacos,
Depuradores de Radicales Libres/farmacología,
Frutas/química,
Litchi/química,
Fenoles/farmacología,
Extractos Vegetales/farmacología,
Sapindaceae/química,
Envejecimiento de la Piel/efectos de los fármacos,
Tamarindus/química
ABSTRACT Geopropolis is a special type of propolis produced by stingless bees. Several pharmacological properties have been described for different types of geopropolis, but there have been no previous studies of the geopropolis from Melipona mondury. In this study, we investigated the antioxidant, antib...
Abstract Phenolic compounds are a group of plant secondary metabolites known to have a variety of bioactivities, including the ability to function as antioxidants. Because of the side effects of the use of synthetic substances, the search for natural and less toxic compounds has increased significantly. ...
