LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Intoxicación por ácido acetilsalicílico, fisiopatología y manejo

Sepúlveda, Rodrigo A; Ortega, Marcos; Donoso, Natalia; Jara, Aquiles.

Rev. méd. Chile; 146 (11), 2018

Acetylsalicylic acid (ASA) intoxication is potentially lethal. After ingestion, AAS is rapidly transformed into salicylic acid that dissociates into an hydrogen ion plus salicylate. Salicylate is the main form of AAS in the body and produces multiple alterations. Initially, the stimulation of the ventila...

Aspirina/metabolismo, Aspirina/envenenamiento, Sobredosis de Droga/fisiopatología, Sobredosis de Droga/terapia, Fibrinolíticos/metabolismo, Fibrinolíticos/envenenamiento, Acidosis/inducido químicamente, Aspirina/administración & dosificación, Sobredosis de Droga/metabolismo, Hipoglucemia/inducido químicamente, Hipotensión/inducido químicamente, Mitocondrias/efectos de los fármacos, Equilibrio Hidroelectrolítico/efectos de los fármacos

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Fibrinolytic protease production by new Streptomyces sp: DPUA 1576 from Amazon lichens

Background Streptomyces sp. DPUA 1576 from Amazon lichens was studied to protease and fibrinolytic production. A 2² factorial experimental design was applied to optimize its protease enzyme production using two independent variables, namely soybean flour and glucose concentrations. Results The optimal c...