This study investigated Yishentongluo Recipe (YSTLF) effects on renal oxidative stress and fibrosis in membranous nephropathy (MN) rats. MN was induced by cationized bovine serum albumin injection. Rats were divided into control, MN, YSTLF, and benazepril groups. After ...
SUMMARY: Aging is an inevitable biological process that affects the function of all organs, including the adrenal gland, which is essential for producing steroid hormones that regulate metabolism, stress response, and immune activation. Understanding how aging affects the morphology of this gland is cruc...
Rafiq, H;
Ayaz, M;
Khan, H. A;
Iqbal, M;
Quraish, S;
Afridi, S. G;
Khan, A;
Khan, B;
Sher, A;
Siraj, F;
Shams, S.
Liver fibrosis is initial stage of any chronic liver disease and its end stage is develops into cirrhosis. Chronic liver diseases are a crucial global health issue and the cause of approximately 2 million deaths per year worldwide. Cirrhosis is currently the 11th most common cause of death globally. Mese...
Abstract This study evaluated the effect of the volatile oil of Alpinia zerumbet (VOAz) on caveolin-1 gene expression and muscular fibrosis. The rats were immobilized to induce fibrosis of the gastrocnemius muscle, and they were treated with VOAz. Collagen quality was assessed by histology and the expres...
Alpinia/química,
Brasil,
Caveolina 1/metabolismo,
Colágeno/metabolismo,
Modelos Animales de Enfermedad,
Fibrosis,
Músculos/efectos de los fármacos,
Músculos/patología,
Aceites Volátiles/farmacología,
Aceites de Plantas/farmacología,
Ratas Wistar
BACKGROUND: The monthly regeneration of human endometrial tissue is maintained by the presence of human endometrial mesenchymal stromal/stem cells (eMSC), a cell population co-expressing the perivascular markers CD140b and CD146. Endometrial regeneration is impaired in the presence of intrauterine adhesi...
Introducción. La enfermedad de Peyronie es una malformación adquirida del pene, originada por la deposición de placas fibróticas en la túnica albugínea. La prevalencia en Estados Unidos oscila entre el 0.39% y 11.8%, en Europa 8.9%, en Latinoamérica no existe un porcentaje puntual de prevalencia a...
SUMMARY: Liver transplantation is the only available method to treat liver failure induced by chronic liver injury. We sought to determine whether the angiotensin-converting enzyme inhibitor, captopril, can inhibit the development of chronic liver injury induced by the hepatotoxic agent thioacetamide (TA...
Captopril/administración & dosificación,
Enfermedad Hepática Inducida por Sustancias y Drogas/tratamiento farmacológico,
Tioacetamida/toxicidad,
Inflamación,
Factor Nuclear 1-alfa del Hepatocito,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Factor de Necrosis Tumoral alfa,
Inhibidores de la Metaloproteinasa de la Matriz,
Actinas,
Western Blotting,
Hígado/efectos de los fármacos,
Inhibidor Tisular de Metaloproteinasa-1,
Metaloproteinasa 9 de la Matriz,
Fibrosis
SUMMARY: Rheumatoid arthritis (RA) that affects the synovial knee joint causes swelling of the synovial membrane and tissue damage. Interleukin-17A (IL-17A) and the enzyme glycogen synthase kinase-3β (GSK3β) are involved in the pathogenesis of RA. The link between IL-17A, GSK3β, the oxidat...
Artritis Reumatoide,
Tiadiazoles/administración & dosificación,
Interleucina-17,
Modelos Animales de Enfermedad,
Glucógeno Sintasa Quinasa 3 beta,
Fibrosis,
Especies Reactivas de Oxígeno,
Actinas,
Ratas Wistar,
Western Blotting,
Colágeno Tipo II/administración & dosificación,
Inmunohistoquímica,
d0077190,
d0154150,
Inmunización
La rinofima es una patología que se caracteriza por presentar hipertrofia de las
glándulas sebáceas con proliferación de tejido fibroso, donde la nariz toma un
aspecto lobulado dando como resultado la deformidad de la punta nasal; es una
forma de rosácea. La prevalencia de esta variedad de rosácea ...
Inflammatory fibrous hyperplasia (IFH) is a common reactive lesion in dental prostheses users that may be associated with chondroid metaplasia (CM). Metaplasia is an adaptive cellular process that may be caused by trauma. We reported here five cases of IFH associated with CM and analyzed morphologically ...
