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Analgesic effectiveness and improvement in quality of life after using topical sevoflurane for an extremely painful anal fissure

Cifuentes-Tébar, Jesús; Rueda-Martínez, Juan Luis; Selva-Sevilla, Carmen; Gerónimo-Pardo, Manuel.
J. coloproctol. (Rio J., Impr.); 41 (2), 2021
Painful anal fissures could be distressing conditions that severely impair the patients' quality of life. The analgesic effectiveness of topical drugs, such as calcium-antagonists and nitrates is quite variable. The inhalational anesthetic sevoflurane is being repurposed as a topical analgesic for painfu...
Fisura Anal/tratamiento farmacológico, Sevoflurano/uso terapéutico, Calidad de Vida, Resultado del Tratamiento, Dolor/tratamiento farmacológico, Analgesia
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Role of micronize purified flavonoid fraction and ethanol Graptophyllum pictum extract on experimental anal ulcer healing. Study on Wistar rat

Prasetyo, Sigit Adi; Wisnu, Yan; Nugroho, Eriawan Agung; Dharmana, Edi; Susilaningsih, Neni; Riwanto, Ignatius.
J. coloproctol. (Rio J., Impr.); 40 (2), 2020
ABSTRACT Aim of the study To evaluate the role of micronized purified flavanoid fraction and ethanol Graptophyllum pictum extract in the treatment of anal ulcer. Method Twenty-eight Wistar rats were randomly allocated into four groups. Groups 2, 3 and 4 the anus were induced with croton oil, but was no...
Fisura Anal/patología, Fisura Anal/tratamiento farmacológico, Flavonoides/uso terapéutico, Plantas Medicinales, Acanthaceae, Aceite de Crotón, Cicatrización de Heridas
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Uso de la nitroglicerina local en el tratamiento de la fisura anal
Local application of nitroglycerin in the anal fissure treatment

Pizarro Núñez, Patricio; Cárdenas de la Maza, René.
Rev. chil. cir; 52 (4), 2000
La fisura anal (FA) es una entidad común, que produce dolor anal en la defecación, en que participa una isquemia relativa del canal anal, asociado a una hipertonicidad esfinteriana. La aplicación tópica de Glicerolato de Trinitrina (GT) produce relajación del esfínter interno, llevando a la cicatri...
Fisura Anal/tratamiento farmacológico, Nitroglicerina/farmacología, Fisura Anal/cirugía, Nitroglicerina/efectos adversos, Nitroglicerina/administración & dosificación, Estudios Prospectivos, Resistencia a Medicamentos, Cefalea/etiología, Resultado del Tratamiento