Arctium lappa L. é indicada no Formulário de Fitoterápicos da Farmacopeia Brasileira para o tratamento de distúrbios urinários leves. Estudos já demonstraram o potencial antioxidante, anti-inflamatório e antidiabético deste extrato, onde foram identificados fenóis, lignanas, taninos e flavonoide...
ABSTRACT Objective Acrylamide is a toxic compound widely used in industrial sectors. Acrylamide causes reactive oxygen species formation and the subsequent lipid peroxidation reaction, which plays an important role in the pathogenesis of oxidative damage. Taxifolin is a flavonoid with antioxidant proper...
BACKGROUND Osteoarthritis (OA) is a form of arthritis due to degradation of articular cartilage. OA is asso ciated with stiffness, joint pain, and dysfunction, affecting adults worldwide. Galangin is a bioactive fla vonoid that exerts several therapeutic and biological activities. Anti-hyperglycemic, ant...
A doxorrubicina (dox) é um medicamento antineoplásico que induz cardiotoxicidade por estresse oxidativo. Os flavonoides são antioxidantes extraídos de plantas como Camellia sinensis e Arrabidaea chica (Fridericia chica). Esta pesquisa objetivou avaliar efeitos protetores do extrato de A. chica (AC), ...
A perda óssea dentária e a formação de lesões periapicais surgem como uma consequênc ia do desequilíbrio da homeostase óssea. Os osteoblastos, juntamente com os osteoclastos e osteócitos, atuam na formação e na reabsorção óssea. Vários marcadores de formação óssea são produzidos por os...
Periodontitis Periapical,
Flavonoides,
Homeostasis,
Huesos,
Osteoblastos,
Osteocitos,
Quercetina,
Resorción Ósea,
Remodelación Ósea,
Rutina,
Flavonoides/toxicidad,
Flavonoides/uso terapéutico,
Flavanonas,
Calcificación Fisiológica,
Osteoclastos
Abstract Clostridium difficile infection (CDI) is the most common hospital acquired diarrheal disease with its increasing incidence and mortality rate globally. DNA Gyrase B (GyrB) is a key component of DNA replication process across all bacterial genera; thus, this offers a potential target for the trea...
ABSTRACT Aim of the study To evaluate the role of micronized purified flavanoid fraction and ethanol Graptophyllum pictum extract in the treatment of anal ulcer. Method Twenty-eight Wistar rats were randomly allocated into four groups. Groups 2, 3 and 4 the anus were induced with croton oil, but was no...
Abstract Background: Cardiovascular diseases, such as acute myocardial infarction, are the main causes of death in the world. The flavonoids present in chocolate can have benefits for people who have risk factors to the development of cardiovascular diseases and have a coadjuvant effect on known therapi...
Estudios Prospectivos,
Infarto del Miocardio/fisiopatología,
Factores de Riesgo de Enfermedad Cardiaca,
Flavonoides/fisiología,
Polifenoles/fisiología,
Cacao,
Flavonoides/uso terapéutico,
Infarto del Miocardio/mortalidad,
Hipertensión,
Diabetes Mellitus,
Tabaquismo,
Infarto del Miocardio/dietoterapia
Osteoartritis/prevención & control,
Osteoartritis/tratamiento farmacológico,
Relación Dosis-Respuesta a Droga,
Flavonoides/farmacología,
Flavonoides/química,
Flavonoides/uso terapéutico,
Estrés Oxidativo/efectos de los fármacos,
Flavonoides/administración & dosificación,
Flavonoides/metabolismo,
Flavonoides/efectos adversos,
Enfermedades Óseas/tratamiento farmacológico
