Reduction of oxidative stress improves insulin signaling in cardiac tissue of obese mice
Einstein (São Paulo, Online); 18 (), 2020
ABSTRACT Objective To evaluate the effects of oxidative stress on insulin signaling in cardiac tissue of obese mice. Methods Thirty Swiss mice were equally divided (n=10) into three groups: Control Group, Obese Group, and Obese Group Treated with N-acetylcysteine. After obesity and insulin resistance w...
Acetilcisteína/farmacología, Glucemia/análisis, Western Blotting, Peso Corporal, Dieta Alta en Grasa, Fluoresceínas/análisis, Depuradores de Radicales Libres/farmacología, Resistencia a la Insulina/fisiología, Miocardio/metabolismo, Estrés Oxidativo/efectos de los fármacos, Estrés Oxidativo/fisiología, Carbonilación Proteica, Especies Reactivas de Oxígeno/análisis, Valores de Referencia, Espectrofotometría