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Development and validation of an HPLC method for the determination of fluorouracil in polymeric nanoparticles

Braz. j. pharm. sci; 49 (1), 2013
The objective of this work was to develop and validate a rapid high performance liquid chromatography (HPLC) method for the quantitative analysis of fluorouracil (5-FU) in polymeric nanoparticles. Chromatographic analyses were performed on an RP C18 column with a mobile phase consisting of acetonitrile a...