Results: 9

Protective effect of polysaccharides isolated from the seeds of Cuscuta chinensis Lam. on 5-fluorouracil-induced intestinal mucositis in mice

Acta cir. bras; 37 (2), 2022
Purpose: To evaluate the protective effect of Cuscuta chinensis Lam. polysaccharides (PCCL) on 5-fluorouracil-(5-FU)-induced intestinal mucositis (IM) in mice. Methods: PCCL was orally administered at a dose of 20 mg·kg–1 for 7 days and its protective effect on 5-FU-induced IM (5-FU, 50 mg·kg–1 fo...

The influence of platelet-rich plasma (PRP) on colonic anastomosis healing impaired by intraperitoneal 5-flourouracil application. An experimental study

Acta cir. bras; 35 (5), 2020
Abstract Purpose 5-flourourasil (5-FU) is commonly used for early intraperitoneal chemotherapy in colorectal or appendiceal cancer patients with peritoneal carcinomatosis. Due to its effect, anastomosis healing can be impaired and leads to anastomotic leakage. In this study, we aimed to investigate the...

5-fluorouracil and cyclophosphamide modify functional activity in submandibular gland of rats

J. oral res. (Impresa); 8 (5), 2019
Objective: Chemotherapy treatment against cancer produce systemic toxicities, among which are those related to important structures of the stomatognathic system and its functional activity. 5 Fluorouracil (5-FU) and cyclophosphamide (Cf) are drugs widely used in solid tumors and in bone marrow transplant...

Amifostine reduces inflammation and protects against 5-fluorouracil-induced oral mucositis and hyposalivation

Braz. j. med. biol. res; 52 (3), 2019
Oral mucositis (OM) is a common and dose-limiting side effect of cancer treatment, including 5-fluorouracil (5-FU) and radiotherapy. The efficacy of the therapeutic measures to prevent OM is limited and disease prevention is not fully observable. Amifostine is a cytoprotective agent with a described anti...

Efeitos da sinvastatina na mucosite gastrointestinal induzida por 5-fluorouracil em ratos

Rev. Col. Bras. Cir; 45 (5), 2018
RESUMO Objetivo: examinar os efeitos da sinvastatina na mucosite gástrica e intestinal após o tratamento com 5-fluorouracil (5-FU), determinados pela expressão de citocinas e histologia em ratos. Métodos: ratos pesando 270±15g foram divididos em dois grupos. O grupo 5-FU+salina foi tratado com 5-F...

Uso do 5-fluorouracil no intra-operatório da cirurgia do pterígio
Intra-operative use of 5-fluorouracil in pterygium surgery

Arq. bras. oftalmol; 63 (2), 2000
Avaliar e efetividade e as complicaçöes com a aplicaçäo do 5-fluorouracil (5-FLU) no intra-operatório da cirurgia do pterígio. Método: Foram avaliados 28 olhos de 26 indivíduos quanto ao tipo e tamanho do pterígio, cirurgias prévias e a resposta ao tratamento cirúrgico (no 7,21,60 e 90 dia de ...

Características histológicas de bolhas filtrantes de pacientes submetidos à trbeculectomia com uso pacientes submetidos à trabeculectomia com uso de 5-FU no intra-operatório
Histologic characteristics of filtering blebs in patients submitted to trabeculectomy with intraoperatively use of 5-FU

Arq. bras. oftalmol; 61 (1), 1998
Os autores avaliaram o aspecto histológico da conjuntiva de bolhas filtrantes de dois pacientes que foram submetidos a revisäo cirúrgica do sítio de filtraçäo após trabeculectomia com uso de 5-fluouracil no intra-operatório. As bolhas foram excisadas devido aos olhos apresentarem hipotonia persis...

Tratamiento médico de 44 pacientes con carcinoma del conducto anal. Intergrupo Argentino para el Tratamiento de los Tumores Gastro-Intestinales (IATTGI)
[Medical treatment of 44 patients with anal canal carcinoma. Argentinian Intergroup for the treatment of gastrointestinal tumors (IATTGI)]

Medicina (B.Aires); 55 (3), 1995
In order to investigate the medical treatment of anal canal carcinoma (ACC), 27 patients (pts) were treated with cisplatin, fluorouracil and radiotherapy, in an alternating schedule. Eleven pts received mitomycin C, fluorouracil and radiotherapy, in a concurrent scheme. Finally, six pts were included in ...

Utilidad de la circuncisión en combinación con 5-fluorouracilo en el tratamiento de la infección subclínica por Papilomavirus humano
Usefulness of circumcision combined with 5-fluoruracil in the treatment of the subclinical infection caused by the human Papilloma virus

Rev. mex. urol; 53 (1), 1993
Resultados de un estudio realizado con el propósito de determinar la utilidad de la circuncisión en combinación con 5-fluorouracilo en el tratamiento de varones sintomáticos con infección subclínica por papilomavirus humano en el surco balanoprepucial y prepucio. Se concluyó que la circuncisión f...