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A comparative study of two separate analytical techniques for the simultaneous determination of diclofenac sodium and diacerein from combined dosage form

Mallick, Sanhita Basu; Chattopadhyay, Helen; De, Amit Kumar; Datta, Sriparna.
Braz. J. Pharm. Sci. (Online); 53 (2), 2017
ABSTRACT Diclofenac sodium (DS) and diacerein (DC) have emerged as a potential combination therapy for the treatment of knee osteoarthritis. Therefore a validated analytical method is essential for the simultaneous estimation of both from combined dosage form. A ratio derivative spectrophotometric and a ...
Estudio Comparativo, Diclofenaco/análisis, Métodos de Análisis de Laboratorio y de Campo, Formas de Dosificación/normas, Cromatografía Líquida de Alta Presión/instrumentación, Análisis Espectral/métodos, Estudio de Validación
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RP-HPLC method development and validation for estimation of rivaroxaban in pharmaceutical dosage forms

Çelebier, Mustafa; Reçber, Tuba; Koçak, Engin; Altinöz, Sacide.
Braz. j. pharm. sci; 49 (2), 2013
Rivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in tablets (Xarelto® (10 mg)). Phenomenex Luna 5 µm C18 100 Å LC Column (250 x 4.6 mm...
Cromatografía Líquida de Alta Presión/métodos, Estudio de Validación, Rivaroxabán/farmacocinética, Indicadores (Estadística), Formas de Dosificación/normas
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Comparison of dissolution profile of extended-release oral dosage forms - two one-sided equivalence test

Lourenço, Felipe Rebello; Ghisleni, Daniela Dal Molim; Yamamoto, Rosa Noriko; Pinto, Terezinha de Jesus Andreoli.
Braz. j. pharm. sci; 49 (2), 2013
The aim of this work is to present the two one-sided test (TOST) as an alternative approach to compare dissolution profiles of extended-release dosage forms. The dissolution profiles of oxycodone extended-release tablets containing 10 mg, 20 mg and 40 mg (reference and generic) were evaluated according t...
Disolución, Formas de Dosificación/normas, Comprimidos/clasificación, Habilidades para Tomar Exámenes/métodos, Equivalencia Terapéutica
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