LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

miR-660-5p promotes breast cancer progression through down-regulating TET2 and activating PI3K/AKT/mTOR signaling

Peng, Bing; Li, Chao; He, Lili; Tian, Mi; Li, Xin.

Braz. j. med. biol. res; 53 (12), 2020

Breast cancer (BC) is a commonly diagnosed cancer in females. MicroRNA-660-5p (miR-660-5p) has been reported to be involved in the occurrence and development of BC. However, the regulatory network of miR-660-5p in BC has not been fully addressed. Quantitative real-time polymerase chain reaction (qRT-PCR)...

Neoplasias de la Mama/genética, Línea Celular Tumoral, Proteínas de Unión al ADN, MicroARNs/genética, Fosfatidilinositol 3-Quinasas/genética, Proteínas Proto-Oncogénicas, Proteínas Proto-Oncogénicas c-akt/genética, Transducción de Señal, Serina-Treonina Quinasas TOR/genética

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