Tityus serrulatus scorpion is responsible for a significant number of envenomings in Brazil, ranging from mild to severe, and in some cases, leading to fatalities. While supportive care is the primary treatment modality, moderate and severe cases require antivenom administration despite potential limitat...
Introducción. Las proteasas y las fosfolipasas son factores de virulencia de Candida spp. que cumplen un papel importante en la invasión de los tejidos. Entre los factores relacionados con el huésped, se encuentran algunos asociados con las características ambientales y otros con la colonización. Ob...
Abstract Candida glabrata infections are responsible for deaths of people globally. Fluconazole is known to be less effective against C. glabrata, which developed many strategies to evade being destroyed by fluconazole. To achieve enhanced efficacy of fluconazole against C. glabrata, the interaction of f...
BACKGROUND: Phospholipase D (PLD) is used as the biocatalyst for phosphatidylserine (PS) production. In general, PLD was expressed in insoluble form in Escherichia coli. High-level soluble expression of PLD with high activity in E. coli is very important for industrial production of PLD. RESULTS: Strepto...
The Malayan blue coral snake, Calliophis bivirgata flaviceps, is a medically important venomous snake in Southeast Asia. However, the complexity and diversity of its venom genes remain little explored. Methods: To address this, we applied high-throughput next-generation sequencing to profile the venom ...
Abstract INTRODUCTION: The aim of this study was to evaluate some virulence factors in Candida albicans isolates from patients with onychomycosis and determine the correlation between these factors and the antifungal resistance profile. METHODS: Seventy species of C. albicans were confirmed using pol...
Antifúngicos/farmacología,
Proteasas de Ácido Aspártico/biosíntesis,
Biopelículas/crecimiento & desarrollo,
Candida albicans/efectos de los fármacos,
Candida albicans/patogenicidad,
Candida albicans/ultraestructura,
Farmacorresistencia Fúngica,
Hemólisis,
Pruebas de Sensibilidad Microbiana,
Microscopía Electrónica de Rastreo,
Uñas/microbiología,
Onicomicosis/microbiología,
Fosfolipasas/biosíntesis,
Reacción en Cadena de la Polimerasa,
Factores de Virulencia
Tityus serrulatus venom (Ts venom) is a complex mixture of several compounds with biotechnological and therapeutical potentials, which highlights the importance of the identification and characterization of these components. Although a considerable number of studies have been dedicated to the characteriz...
Abstract INTRODUCTION: Candida parapsilosis complex species, frequently found in hospital environments, have gained importance as etiological agents of candidemia. METHODS: Candida parapsilosis complex isolates from a nosocomial environment were identified and their hydrolitic enzyme activity and abili...
Abstract Pulpal and periodontal tissues have similar microbiota that allows cross-contamination between the pulp and periodontal tissues. Objective The aim of this study was to investigate the prevalence of isolated Candida albicans from periodontal endodontic lesions in diabetic and normoglycemic pati...
Candida albicans/aislamiento & purificación,
Candida albicans/patogenicidad,
Estudios de Casos y Controles,
ADN de Hongos,
Cavidad Pulpar/microbiología,
Enfermedades de la Pulpa Dental/diagnóstico por imagen,
Enfermedades de la Pulpa Dental/microbiología,
Enfermedades de la Pulpa Dental/fisiopatología,
Diabetes Mellitus Tipo 2/microbiología,
Diabetes Mellitus Tipo 2/fisiopatología,
Electroforesis,
Interacciones Hidrofóbicas e Hidrofílicas,
Oxidación-Reducción,
Péptido Hidrolasas/análisis,
Enfermedades Periodontales/diagnóstico por imagen,
Enfermedades Periodontales/microbiología,
Enfermedades Periodontales/fisiopatología,
Bolsa Periodontal/microbiología,
Fosfolipasas/análisis,
Reacción en Cadena de la Polimerasa,
Radiografía Dental,
Estadísticas no Paramétricas,
Virulencia
Abstract Objective Candida albicans is the primary causative agent of oral candidosis, and one of its key virulent attributes is considered to be its ability to produce extracellular phospholipases that facilitate cellular invasion. Oral candidosis can be treated with polyenes, and azoles, and the more ...
Antifúngicos/farmacología,
Candida albicans/efectos de los fármacos,
Candida albicans/metabolismo,
Candidiasis Bucal/microbiología,
Fosfolipasas/biosíntesis,
Antifúngicos/uso terapéutico,
Azoles/farmacología,
Azoles/uso terapéutico,
Candida albicans/patogenicidad,
Candidiasis Bucal/tratamiento farmacológico,
Dentaduras,
Diabetes Mellitus,
Equinocandinas/farmacología,
Activación Enzimática,
Espacio Extracelular,
Pruebas de Sensibilidad Microbiana,
Polienos/farmacología,
Polienos/uso terapéutico,
Fumar,
Factores de Virulencia,
Candida albicans/aislamiento & purificación
