To study the effect of 50% ethanol extract of
Bougainvillea xbuttiana
on the enzymatic
activity, cell via
bility and cytokine production provoked by the venom of
Bothrops jararaca
in macro
-
phages. Three assays were used to study the effects of
B. xbuttiana
extract on the dama...
Extractos Vegetales/farmacología,
Venenos de Crotálidos/antagonistas & inhibidores,
Macrófagos/efectos de los fármacos,
Nyctaginaceae/química,
Citocinas,
Ensayo de Inmunoadsorción Enzimática,
Etanol,
Fosfolipasas A2,
Ratones Endogámicos BALB C,
Venenos de Crotálidos/enzimología,
Supervivencia Celular/efectos de los fármacos
Achyrocline satureioides is popularly known for its richness in phenolic compounds and medicinal properties (anti-inflammatory, analgesic, and hepatoprotective). The present study aimed at broadening the knowledge about the pharmacological potential exerted by the aqueous and ethanolic extracts of A. sat...
Background: Naja atra is a venomous snake species medically relevant in China. In the current study, we evaluated the composition and toxicological profile of venom collected from farm-raised N. atra. Methods: Venom was collected from third-generation captive bred N. atra on a snake farm in Hunan Provi...
Moraes, Jeane do Nascimento;
Francisco, Aleff Ferreira;
Dill, Leandro Moreira;
Diniz, Rafaela Souza;
Oliveira, Claudia Siqueira de;
Silva, Tainara Maiane Rodrigues da;
Caldeira, Cleópatra Alves da Silva;
Corrêa, Edailson de Alcântara;
Coutinho-Neto, Antônio;
Zanchi, Fernando Berton;
Fontes, Marcos Roberto de Mattos;
Soares, Andreimar Martins;
Calderon, Leonardo de Azevedo.
Background
Cathepsin D (CatD) is a lysosomal proteolytic enzyme expressed in almost all tissues and organs. This protease is a multifunctional enzyme responsible for essential biological processes such as cell cycle regulation, differentiation, migration, tissue remodeling, neuronal growth, ovulation, an...
Background: In the present study, we have tested whether specimens of the medically relevant scorpion Tityus pachyurus, collected from two climatically and ecologically different regions, differ in the biological activities of the venom. Methods: Scorpions were collected in Tolima and Huila, Colombia. C...
Abstract Introduction: Snakes of the genus Micrurus have fossorial habits, passive temperament and scarce production of powerful venom with neurotoxic characteristics that block the synaptic transmission at the neuromuscular junction. Objective: To present an overview of the neurotoxicity of the Micrur...
Abstract Background: Endogenous phospholipase A2 inhibitors from snake blood (sbPLIs) have been isolated from several species around the world, with the primary function of self-protection against the action of toxic phospholipases A2. In American snakes, sbPLIs were solely described in pit vipers, in ...
Argenteohyla siemersi (red-spotted Argentina frog) is a casque-headed tree frog species belonging to the Hylidae family. This species has a complex combination of anti-predator defense mechanisms that include a highly lethal skin secretion. However, biochemical composition and biological effects of this ...
Hatakeyama, Daniela Miki;
Tasima, Lídia Jorge;
Bravo-Tobar, Cesar Adolfo;
Serino-Silva, Caroline;
Tashima, Alexandre Keiji;
Rodrigues, Caroline Fabri Bittencourt;
Aguiar, Weslei da Silva;
Galizio, Nathália da Costa;
Lima, Eduardo Oliveira Venancio de;
Kavazoi, Victor Koiti;
Gutierrez-Marín, Juan David;
Farias, Iasmim Baptista de;
SantAnna, Sávio Stefanini;
Grego, Kathleen Fernandes;
Morais-Zani, Karen de;
Tanaka-Azevedo, Anita Mitico.
Variability in snake venoms is a well-studied phenomenon. However, sex-based variation of Bothrops atrox snake venom using siblings is poorly investigated. Bothrops atrox is responsible for the majority of snakebite accidents in the Brazilian Amazon region. Differences in the venom composition of Bothrop...
Silva-Júnior, Leandro Norberto da;
Abreu, Lara de Souza;
Rodrigues, Caroline Fabri Bittencourt;
Galizio, Nathália da Costa;
Aguiar, Weslei da Silva;
Serino-Silva, Caroline;
Santos, Valdomiro Souza dos;
Costa, Isabella Alves;
Oliveira, Luis Vicente Franco;
SantAnna, Sávio Stefanini;
Grego, Kathleen Fernandes;
Tanaka-Azevedo, Anita Mitico;
Rodrigues, Leandro Nascimento da Silva;
Morais-Zani, Karen de.
South American rattlesnakes are represented in Brazil by a single species, Crotalus durissus, which has public health importance due to the severity of its envenomation and to its wide geographical distribution. The species is subdivided into several subspecies, but the current classification is controve...
