Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model
Braz. j. med. biol. res; 51 (5), 2018
Gastroschisis (GS) is an abdominal wall defect that results in histological and morphological changes leading to intestinal motility perturbation and impaired absorption of nutrients. Due to its anti-inflammatory, antioxidant, and neuroprotective effects, cannabidiol (CBD) has been used as a therapeutic ...
Antiinflamatorios/uso terapéutico, Cannabidiol/uso terapéutico, Modelos Animales de Enfermedad, Enteritis/prevención & control, Enfermedades Fetales/metabolismo, Enfermedades Fetales/patología, Gastrosquisis/metabolismo, Gastrosquisis/patología, Inmunohistoquímica, Intestinos/efectos de los fármacos, Nitratos/metabolismo, Óxido Nítrico Sintasa de Tipo II/análisis, Nitritos/metabolismo, Ratas Sprague-Dawley